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Seizure-Definition
Aberrant cortical neural pathway activation
Motor activity
Sensory activity
Mixed
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Status epilepticus
Long lasting
Life threatening
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other seizures, e.g grand mal (life threatening ???)
no
but have to notice the time length that could indicate status epilepticus
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Seizure - Pathophysiology
Focal source of excessive neuronal electrical discharge in the brain
Cause:
Epilepsy
Head trauma
Fever (quick change in body temp --> feverile seizure)
ETOH withdrawal
Hypoxia (birth, syncope)
Stroke
Brain tumor Meningitis
Local anesthetic overdose Hypoglycemia
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Seizure - possible cause
Epilepsy
Head trauma
Fever (quick change in body temp --> feverile seizure)
ETOH withdrawal
Hypoxia (birth (inc chance of having epilepsy later on), syncope)
Stroke
Brain tumor
Meningitis
Local anesthetic overdose *** (for dentist)
Hypoglycemia
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Seizure-Pathophysiology: types
--Generalized seizures spread to entire brain
Absence (froze completely for a short time) or petit mal seizures
Tonic/ clonic or grand mal seizures
- --Partial seizures remain focal and
- localized
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Treatment of Epilepsy
Medications
Vagal nerve stimulation
Ketogenic diet
Neurosurgery
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Medications
Barbiturates
Benzodiazepines
Hydantoins
Succinimides
Others (carbamazepine, felbemate, gabapenin, lamotrigine. levetiracetam, oxcarbazepine, valproic acid, zonisamide)
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Vagal Nerve Stimulation
Spontaneous discharge (periodically)
Patient-controlled discharge (aura prior to seizure)
when med fails
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Ketogenic Diet
Used mostly in children
- About one third who try it become
- completely or near-completely seizure free
- Another third still have seizures,
- but with many less and with less medical therapy
- The remainder do not respond, or
- find it too hard to continue the diet.
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Seizure-Risk Factors
Patients with a history of seizures
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Question to ask pt with history of seizure
Frequency (1x or 2x a week --> high chance of having seizure)
Last seizure?
Precipitating factors (stress?)
- Medications:
- last time serum drug levels were checked (could varied)
- Changes in medications since last check (the more change, the high the chance of having seizure)
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Inc chance of having seizure with pt who has history of seizure
- 1x or 2x per week
- no change in med
- normal drug serum level
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Seizure-Precipitating Factors
Failure to comply with medications (no stopping abruptly, waning. if not, result in status epilepticus)
Stress
Other emergency conditions
Flashing lights
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Failure to comply with med result in
status epilepticus
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Seizure-Prevention
Confirm that patient has taken anti-seizure medications on day of procedure
Limit stress: Sedation, Benzodiazepines, Barbiturates
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Seizure-Recognition
Prodromal phase with personality changes
Aura, depends on the location of the initiating seizure focus (smell, visual)
Loss of consciousness
Ictal phase (tonic-clonic phase)
Post-ictal phase
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Seizure - recognition: post ictal phase
need to control airway
reassurance
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Seizure-Treatment
Stop dental treatment
all objects out of mouth
- Remove dangerous items from around
- patient
Gently restrain and protect patient during ictal phase
- Nothing placed in the patient’s
- mouth
Let the seizure run its course
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Seizure-Treatment
- ---Supportive therapy during post-ictal phase
- Maintain airway
- Oxygen
- Monitor vital signs
---Consider 911, especially if seizure continues or repeats
---Possible valium 5-10 mg IV or midazolam 2-4 mg IV / IM if seizure continues or repeats
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Call 911 is a must after the pt has seizure (true or false)
false
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Pt with seizure for the 1st time or haven't had one in a year or change blood serum. Call 911
(true or false)
true
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When to phone 911: No need for assistance
-----No need for assistance:
If a known epileptic patient (medical I.D.)
If seizure ends in less than 5 minutes
If normal consciousness returns
If there is no physical injury
If not pregnant or diabetic
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When to phone 911: An ambulance should be called
If the seizure happened in water
If it’s a first time seizure
- If the person is not known to have
- epilepsy
- vIf the person is pregnant, injured
- or diabetic
- vIf the seizure lasts more than 5
- minutes
- If a second seizure starts shortly
- after the first
- If consciousness does not start to
- return shortly after the ictal
- phase
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