Pharm ATI EXAM

  1. Action of SSRI?
    allows more serontonin to be at receptor
  2. Pt teaching about AE of SSRI's?
    early s/s will subside

    N, diaphoresis, tremor, fatiuge, drowsiness
  3. AE of SSRI's?
    • 1. sexual dysfunction
    • 2. weight gain
    • 3. GI bleeding
    • 4. hyponatremia esp in elderly
    • 5. rash that will go away if stop med
  4. S/S of serontonin syndrome?
    • 1. agitation
    • 2. confusion
    • 3. anxiety
    • 4. hallucinations
    • 5. hyperreflexia
    • 6. incoordination
    • 7. tremors & fever
    • 8. diaphoresis
  5. When does serontonin syndrome usually occur?
    2 to 72 h after initiation of Tx
  6. Serotonin withdrawal syndrome?
    nausea, sensory disturbances, anxiety, tremor, malaise, unease

    should taper off the med
  7. SSRI CI?
    • 1. liver or renal dysfunction
    • 2. seizure disorders
    • 3. Hx of GI bleeding
  8. SSRI interactions?
    use with MAOI or TCA can cause serotonin syndrome
  9. How long before antidepressants work?
    can take 1 to 3 weeks & up to 3 months for full effects
  10. EX of TCAs?
    • 1. amitriptyline
    • 2. nortriptyline
    • 3. imipramine
    • 4. amoxapine
    • 5. trimipramine
    • 6. doxepin
  11. Action of TCAs?
    increase NE & serotonin at synapse
  12. 5 AE of TCAs?
    • 1. orthostatic hypotension
    • 2. anticholinergic effects
    • 3. sedation
    • 4. decreased seizure threshold
    • 5. diaphoresis
  13. Anticholinergic effects?
    • 1. dry mouth
    • 2. blurred vision & phtophobia
    • 3. urinary retention
    • 4. constipation
    • 5. tachycardia
  14. CI for TCAs?
    seizure disorders
  15. Cautious use of TCAs?
    • 1. CAD
    • 2. DM
    • 3. liver, kidney, or resp disorders
    • 4. urinary retention & obstruction
    • 5. glaucoma
    • 6. benign prostatic hypertrophy
    • 7. hyperthyroidism
  16. Drug interactions with TCAs?
    use of MAOIs or St John's Wort may lead to serotonin syndrome
  17. 5 SSRIs?
    • 1. prozac
    • 2. paxil
    • 3. celexa
    • 4. lexapro
    • 5. zoloft
  18. SSRIs not good for pregnancy?
    prozac & paxil
  19. EX MAOIs?
    • 1. nardil
    • 2. marplan
    • 3. parnate
    • 4. emsam
  20. Action of MAOIs?
    increase dopamine, serotonin, & NE in the brain
  21. AE of MAOIs?
    • 1. CNS stimulation - anxiety, mania
    • 2. orthostatic hypotention
    • 3. hypertensive crisis if eat tyramine
Author
mthompson17
ID
225291
Card Set
Pharm ATI EXAM
Description
pharmacology for nursing ATI standardized Exam
Updated