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Embryonic Age?
266 from fertilization
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Menstrual Age?
40 weeks from first day last cycle
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Embryonic Period
up to 8 weeks after fert.
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Fetal Period?
9th week til birth
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CMV
Calcifications, Mental retardation, Micro/ HydroceValy
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Herpes
Microcephaly, retinal dysplasia
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Rubella
congenital heart defects, deafness, cataracts, glaucoma
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Varicella
retardation, muscle atrophy
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toxoplasma
calcifications,micro, hydro, MR
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treponema
MR, deafness, hydrocephalus, teeth and bone problems
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Alcohol
FAS: IUGR, MR, microcephaly, short palpebral fissure
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Aminopterin
IUGR, CNS/ skeletal defects
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Busulfan
organ hypoplasia, stunted growth, cleft palate
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phenytoin
IUGR, MR, microcephaly, broad nasal bridge, phalangeal hypoplasia, inner epicanthal folds
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lithium
heart and large vessels
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Retinoic Acid (A)
neural tube, Face
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Tetracycline
stained teeth
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Radiation
MR, skeletal, microcephaly
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Kleinfelders
sterile, small testes, long lower limbs, low IQ, gynecomastia, XXY
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Turners
45, XO, short, webbed neck, broad chest, wide nipples, lyphedema, no sexual maturity
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Down's
flat nasal bridge, slanting eyes, Older Mothers, Alpha protein low, MR, ASD
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Thalidomide
Amelia, Phocomelia, hypoplasticity, facial palsy, herat defects
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Warfarin
small noses, hydrocephalus, MR, Clefting
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Folic Acid
Neural Tube Defects
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Maternal Diabetes
large baby, neonatal hypoglycemia, still born
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Renal Agenesis
failure of ireteric bud to reach metanephros
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Menstrual Phase
- 4-5 days...discharge
- m, p, s
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Proliferative phase
9 days. dependent on estrogen from ovarian follicle
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Secretory phase
13 d. progesterone from corpus lutem
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