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Phenergan
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Phenergan
Names / Class
Promethazine
Phenothiazine Antihistamine (H1 antagonist)
Phenergan / Promethazine
Mechanism of Action
Mild anticholinergic activity
Antiemetic
Potentiates actions of analgesics
Completely blocks histamine receptors
Phenergan / Promethazine
Onset of Action
Peak Effects
Duration
Half-Life
5 minutes (IV)
Varies
4 - 6 hours
10 - 14 hours
Phenergan / Promethazine
Indications
Nausea & Vomiting
Motion Sickness
Sedation
To potentiate the effects of analgesics
Phenergan / Promethazine
Contraindications
Comatose states
Pts who have received large amts of depressants (including ETOH)
Phenergan / Promethazine
Precautions
Avoid accidental intraarterial injection
Extravasation can cause tissue damage ("Black box" warning)
Phenergan / Promethazine
Side Effects
May impair mental & physical ability
Drowsiness
Phenergan / Promethazine
Adult Dose
12.5 - 25 mg IV or IM
Phenergan / Promethazine
Pedi Dose
0.5 mg/kg IV
Phenergan / Promethazine
Max Dose
25 mg
Phenergan / Promethazine
Routes / How Supplied
IV
Deep IM
Unknown (vial?)
Author
Ritameeker
ID
224769
Card Set
Phenergan
Description
Phenergan
Updated
2013-07-25T15:10:55Z
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