ID: Viruses

  1. how do viruses get into a host cell?
    • Viral replication is dependent on the specificity of virus binding to a particular host tissue
    • Specific structures on the virus recognize receptors on the host cell surface
    • Once attached, the virus must penetrate the host cell
  2. what happens when viruses get inside?
    • Uncoating occurs
    • This is followed by using host machinery to transcribe viral RNS into proteins needed to make more¬†virus
    • Antiviral drugs target a viral enzyme¬† or protein needed by the virus but not the host
  3. immunocompromised immune systems and viruses:
    • A competent immune system will be able to eliminate or control a viral infection
    • The immunocompromised, such as AIDS, transplant or cancer patients are more likely to have frequent viral infections
  4. how do antivirals work?
    • Must possess the ability to enter cells infected with a virus
    • The ability to interfere with viral binding, RNA, DNA or protein synthesis
  5. small sampling of viral infections:
    (type of infections we will be treating with these drugs)
    • Herpes simplex
    • Varicella zoster
    • Cytomegalovirus (CMV)
    • Influenza
    • HIV
Card Set
ID: Viruses