-
Nitroglycerin
(a) Name
(b) Classification
- (a) Nitroglycerin, Nitrostat, Nitrolingual
- (b) Vasodilator
-
Nitroglycerin
Action
- Causes systemic dilation of arteries and
- veins
- Decrease myocardial workload and O2
- demand by reducing preload and
- afterload
- Increases myocardial perfusion by dilating coronary arteries
-
Nitroglycerin
(a) Indications
(b) Contraindications
- (a) Chest pain of myocardial origin
- Pulmonary edema associated with
- cardiogenic shock
- (b) Poor sytemic perfusion (BP<90)
- Use of phosphodiesterase inhibitors
- (Viagra, Levitra (24hrs), Cialis (48hrs)
- etc.
- Patients with suspected cerebral
- hemorrhage
-
Nitroglycerin
Adverse Effects
- Cardiovascular
- Hypotension
- Brady/Tachycardia
- Gastrointestinal Nausea/Vomiting
- Dry mouth
- Sublingual burning
- Neurological Headache
- Dizziness
- Confusion
- Blurred Vision
- General Flushed
-
Nitroglycerin
Administration
0.4mg (1spray) every 5 mins SL (BP>90)
-
Nitroglycerin
Pediatric
Not recommended
-
Nitroglycerin
(a) Onset
(b) Duration
- (a) 1-3 mins
- (b) 30-60 mins
-
Nitroglycerin
Precautions
- Monitor patient for onset of hypotension
- May have synergistic effect in patients taking
- beta blockers or calcium channel blockers
- Do not shake container, it will alter dose
- delivered
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