-
What is the most common location of an Intraparenchymal hemorrhage?
Basal ganglia and thalamus 65%
-
What is the most common cause of cerebral hemorrhage?
Hypertension
-
What might a patient be diagnosed with if they present with sudden loss of consciousness, hemiplegia, convulsions, coma?
Parenchymal hemorrhage
-
What type of hemorrhage occurs with a berry aneurysm?
Subarachnoid hemorrhage
-
What is the most common cause of a subarachnoid hemorrhage?
Berry aneurysm
-
What is the symptomology of a subarachnoid hemorrhage?
- Headache
- Nuchal rigidity
- Altered mental status
- Hydorcephalus (if blockage occurs)
-
What vein is most vulnerable to a subdural hemorrhage?
Superior Cortical Veins
-
What is the most common cause of a subdural hemorrhage?
Trauma
-
What artery is commonly injured by a skull fracture and what type of hemorrhage does it cause?
- Middle meningeal artery
- Epidural Hemorrhage
-
What percent of Berry aneurysms occur within the carotid supply?
90%
-
What type of aneurysm is most common in subacute bacterial endocarditis. It can spread infection into the subarachnoid space and cause leptomeneningitis and brain abscess?
Mycotic (Septic) Aneurysm
-
Where do most thrombosis cause damage in the brain?
Basal ganglia
-
Where does atherosclerosis most commonly appear first in the brain?
Carotid artery
-
What percentage of adults have experienced a severe or disabling headache at least once?
45%
-
Where is headache pain referred from the brain parenchyma?
None it does not produce pain
-
What type of headache is caused by muscle spasm, irritation of nasal and accessory structures, and eye disorders?
Extracranial
-
What type of headache causes extreme pain over the entire head?
Headache of meningitis
-
What type of headache is caused by a lumbar puncture?
Intracranial (low CSF pressure)
-
What is another name of a classical headache?
Migraine with aura
-
Are migraines unilateral or bilateral?
Unilateral
-
What type of headache presents with pain around one eye, tearing of eye, ptosis, stuffy nose, temporal pain?
Cluster headache
-
What type of headache presents with an abrupt elevation in BP, Tachycardia, palpitations, sweating, tremor, sense of apprehension?
Headache due to Pheochromocytoma
-
where are neurofibrillary tangles found in alzheimer's disease?
Intracellular fluid
-
Where are neuritic plaques found in alzheimer's disease?
Extracellular fluid
-
What areas of the brain are atrophied in Pick's disease?
frontal and temporal lobes
-
In what disease would one see lewy bodies?
parkinson's disease
-
What are the parts of the corpus callosum?
- Rostrum:ant tip of canoe
- Genu:
- Trunk:
- Splenium:
-
What type of fibers synapse with the anterior lobe of the cerebellum?
- Spinocerebellar
- - Golgi tendon, muscle spindle
-
What type fibers synapse with the posterior lobe of the cerebellum?
- Cerebrocerebellar
- - Conscious movement
-
What type of fibers synapse with the folliculonodular lobe of the cerebellum?
- vestibulocerebellar
- - balance and eye movement
-
What are the three layers of the cerebellum?
- Molecular layer (outer)
- Purkinge layer (primary ouput of cerebellum
- Granular (deep)
-
What are the fibers of the spinocerebellar and pontocerebellar tracts called?
Mossy Fibers
-
What is caused by denaturing of proteins of the lens of the eye? (inability to accommodate)
Presbyopia
-
What is hyperopia and what is the correction?
- It is farsightedness caused by focal point being behind the retina
- Convex lense
-
What is Myopia and what is the correction?
It is nearsightedness (focal point in front of retina)
Concave lense
-
What is the correction for astigmatism?
Spherical lense
-
A rare neurologic disorder that impairs autonomic function and has parkinsonian symptoms
What is Multiple System Atrophy (shy-drager syndrome)
-
Atrophy of Caudate nucleus, frontal and temporal gyri
what is huntingtion's disease
-
What chromosome is the mutant gene for Huntington's disease found on?
chromosome 4
-
Individuals having more than 40 repeating CAG sequences
what is huntington's disease
-
what is the probable mechanism of cell death in Huntington's disease?
Glutamate excitotoxicity
-
Beta-hemolytic strep infection (rheumatic fever) is precursor. Typical onset of 5-15 yrs of age. 3-6 month duration of chorea?
Sydenham's Chorea (St. Vitus' Dance)
-
Mutation of long arm of chromosome 13. Symptoms: Tremor, diminished dexterity, unsteady gate, rigidity, Kayser-Fleischer ring?
- Wilsons Disease (hepatolenticular)
- Improper copper metabolism
- symptoms depend on deposit in lenticular nucleus
-
What movement is seen in globus pallidus lesion?
Athetosis (worm like hand eye neck)
-
Where is the lesion most likely in hemiballismus?
- Subthalamus
- Hemiballismus (violent movements)
-
Where is the lesion most likely in Chorea (quick jerky movments face and limbs)
Putamen
-
How does dopamine affect the direct and indirect pathways respectively?
- Direct = excitatory
- Indirect = inhibitory
- overall = excitatory
-
CSF findings: Clouded, increased pressure, increase in neutrophils, increased protein, absence of sugar (eaten by bacteria), presence of organism
Suppurative meningitis (leptomeningitis)
-
What type of infection would you see CSF with: increase in lymphocytes and proteins, normal glucose?
Viral meningitis
-
Rapidly fatal dementia, pyramidal and extrapyramidal symptoms, severe atrophy of brain; intense astrocytosis in cerebral cortex, caudate, putamen.
Creutxfeldt-Jakob Disease
-
What is the anatomical presentation of prion diseases?
spongiform encephalopathy
-
Papovavirus that infects oligodendrocytes
Symptoms: hemiparesis, intellectual impairment, blindness, aphasia, death 3-6 months
Progressive multifocal leukoencephalopathy
-
Type of meningitis narrowing and obliteration of subarachnoid space due to trabeculae formation leading to hydrocephalus
Acute suppurative meningitis
-
Onset is insidious, anorexia and weightloss.
CSF contents: lymphocytes, increased protein, decreased glucose, tubercle bacilli
Tubercculous menningitis
-
Associated with prior measles infection
multifocal areas of neuronal, destruction and gliosis fatal in 1-2 years.
Subacute sclerosing panencephalitis
-
What is the most common demylination disease?
Multiple sclerosis
-
What area if the spinal cord is most commonly affected by Multiple sclerosis?
Cervical
-
CSF FINDINGS: increased lymphocytes and Ig levels, normal glucose levels, oligoclonal immunoglobulin bands
Multiple sclerosis
-
A patient presents with scanning speech, intention tremor, nystagmas what is your initial diagnosis?
Multiple Sclerosis (classic triad)
-
What viral infections are associated with acute disseminating encephalomyelitis
- measles
- mumps
- rubella
- chickenpox
-
What disease involves demyelination of the peripheral nerves?
- Guillian -Barre syndrome
- (demyelination occurs inferior to superior)
-
CSF Findings: Albumino-cytoogic dissociation of CSF, greatly increased protein, slightly increased cell count
Gullian-Berry syndrome
-
CN VII Upper motor neuron (ipsilateral or contralateral)
Contralateral
-
Where is the lesion: ipsilateral facial paralysis, loss of tast over anterior two thirds of tongue, hypercousis?
Facial canal
|
|