The incidence of perioperative death with ES is ___, and the rate of maternal mortality is ____.
19%
45-60%
What occurs with increased FiO2 and what should be considered with ES pt's?
pulm vasodilation with increased O2 will decrease shunt fraction in normal patients. O2 causes VASODILATION!
Why is NO pathway used for ES? what drugs are used in this category?
increased cGmp causes smooth muscle relaxation
Viagra/cialis
Describe Epoprostenol.
prostacyclin analogue, direct dilator but must have continuous infusion
Describe Bosentan:
endothelin receptor antagonist.
Can decrease PVR by 25%.
oral takes months to work and decreases effectiveness of oral contraceptives.
_________ are used with O2 therapy to cause _______ __________.
bronchodilators
pulmonary vasodilation
____ ________ are contraindicated in ES pt's.
Pace Makers
What complications are seen with ES?
bleeding disorders- ^ PT PTT
renal dysfunction-
Hemoptysis
Cholelithiasis
Hypertrophic Osteoarthropathy- seen in ankles.
Gout
CVA
What decreases are seen in the pulmonary system?
lung capacity
vital capacity
FEV
peak exp flow rate
Compliance
What increases are seen in the pulmonary system?
residual volume
closing lung volume
increasd ___ pressure should be avoided with ES. what other things will increase PVR and shunt fraction?
LA
hypercarbia
hypoxia
acidosis
increased pulm blood flow
what things should be avoided with ES?
myocardial depression
extreme HR changes
decreased venous return
volume overload
keep the shunt ________. Causes of increased R L shunt are:
balanced
decreased SVR
increased PVR
avoid ____ _______. ___ drugs will work ____ and inhalational drugs will work _____. Be careful with fluid titration bc lowered tolerance for pre-load and afterload. RBC threshold is _______. Avoid Pain.
air embolism
IV
fast
slow
increased
should you use a Pulm artery catheter in ES?
risks outweigh benefits.
Bosentan and EPoprostenol can prolong what drugs?
NDMR
What two things should be kept low with ES?
Co2, pip
AHA antiboitic IE prophylaxis for CHD with low O2 levels, not fully repaired and surgical shunt or conduit.
also with any residual effects if repaired or recently repaired
Spinal may cause ________, and should not be done.
sympathectomy
max insufflation pressure for laparoscopic surgery _____. should do open when possible.
14 mmhg
ES will show high ___ > ___%
Hct
60
How can shunt be monitored in a pt with ES due to PDA?
L foot will have a lower sat bc descending aorta is post-ductal