Pharmacokinetics & Pharmacodynamics part 2

  1. T/F: Giving a smaller dose of a drug will decrease the half-life.
    • False. 
    • Image Upload 1
  2. T/F: Concentration of the steady state, and how quickly we achieve it is independent of frequency of dosing.
    • True. 
    • Image Upload 2
  3. Name three drugs that have a rapid onset of action.
    • remifentanil
    • alfentanil
    • propofol
  4. Which drugs have a slower onset of action?
    • Midazolam
    • Fentanyl

    "Mother Fuc$er!" Why isn't this drug working yet?
  5. Why does alfentanil have a quicker onset of action than fentanyl or sufentanil?
    It is 89% nonionized- so it gets to the brain faster.
Card Set
Pharmacokinetics & Pharmacodynamics part 2
From the second half of Pharm 3 lecture (summer 1)