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USMLE Heme-onc
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Reed-Sternberg cells surface proteins
CD30, CD15
t(8;14)
c-myc
Burkitt's lymphoma
t(11;14)
Mantle cell lymphoma
CD5+
t(14;18)
bcl-2 oncogene expression
Follicular lymphoma
Molecular problem for HTLV-1 associated t-cell lymphoma
TAX inhibits p53
Waldenstrom's macroglobulinemia
M spkie and hyperviscosity symptoms
No lytic bone lesions
Most common Igs for multiple myeloma
IgG
IgA
Findings in multiple myeloma
Hypercalcemia
Renal insufficiency from nephrocalcinosis
Anemia
Bone/Back pain
t(12;21)
Means better prognosis in ALL
ALL marker
TdT+
Smudge cells
SLL/CLL
TRAP positive
Hairy cell leukemia
Auer rods
AML
Responds to all-trans retinoic acid
AML M3
t(9;22)
CML, bcr-abl
Auer rods are ____-positive
Peroxidase
t(11;22)
Ewing's sarcoma
Birbeck granules
tennis rackets on EM for langerhans cell histiocytosis
S-100 and CD1a
Langerhans cell histiocytoses
CD1+
Langerhans cell histiocytoses
Skin involvement
Langerhans cell histiocytoses
Disorders with positive JAK2
Polycythemia vera
Essential thrombocytosis
Myelofibrosis
Author
andresjm
ID
22017
Card Set
USMLE Heme-onc
Description
Heme-onc for Step 1 from FA 2010
Updated
2010-06-04T19:17:30Z
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