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Gram Stain appearance?
Small GPB, often presenting as cocco-bacillary, pleomorphic, pallisades or chinese letter like appearance.
Small, grayish white may or may not be hemolytic
Tellurite Cysteine Agar CTBA:
Small Black colonies
Grayish black colonies with a brown halo
Nitrate & Catalase
Esculin & Motilitiy
: (tests for toxin phage
: culture and antitoxin in rabbit
Usually presents as a repiratory disease or occasionally cutaneous inf.
Spread person to person
Rare due to vaccinations.
Pathogenesis & virulence factors
: bacterai colonize and proliferate in local tissues of the throat creating pseudomembrane.
: Bacteria produce an exotoxin which causes the death eukaryotic cells and tissues by inhibition of cell protein systhesis.
Penicillin or erythromycin
Normal on skin
disease causing in some immunocompromised or noscomial
Line related infections