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MIC 541-Exam 5-Virology 18
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What percent of pediatric respiratory infections are due to Adenovirus?
5-8%
What percent of pediatric gastroenteritis is caused by Adenovirus?
4-15%
How is adenovirus spread?
respiratory and ocular secretions
Fecal-oral route
What are severe cases of Adenovirus treated with?
Interferon
What type of vaccine is available for adenoviruses?
Inactivated polyvalent vaccine
What are the elongated structures that stick off the side of the adenovirus?
Penton
How does Adenovirus enter the host cell?
Endocytosis
Where does adenovirus replicate in the host cell?
in the Nucleus
Where is the Adenovirus assembled in the host cell?
In the nucleus
Describe the general features of Papilloma and Polyoma viruses?
Small non-encapsulated double stranded DNA
Short circular DNA
Causes persistent infections and tumors
What do Papilloma viruses cause?
squamous epithelial growth = warts = verruca
How many different strains of HPV cause Papillomas?
100+
What is HPV?
Human Papilloma virus
What is a common seed wart?
painless elevated rough growth
Usually on fingers
What are Plantar warts?
Deep painful wart on the bottom of feet
What are genital warts?
morphology ranges from tiny flat bumps to extensive branching cauliflower like masses
What is the most common STD in the US?
Genital warts/caused by HPV
How is HPV transmissible?
Direct contact
Fomites
What is the incubation period for HPV?
2 weeks to more than a year
What does HPV replication depend on?
The stage of epithelial cell differentiation
What does the stage of epithelial cell differentiation effect in HPV?
HPV replication
What are the genital warts caused by HPV called?
Condyloma acuminata
What are the histological indicators of HPV on a pap smear slide?
Koliocyte
What is a Koliocyte?
An indicative cell for HPV found on a pap smear
How many HPV types increase the risk for developing reproductive cancer?
9
How many HPV viruses account for 70% of metastatic tumors
2
How can warts be romoved?
Most regress on their own
Chemical removal
: podophyllin
Physical removal
: cauterization, freezing and laser surgery
What is podophyllin used to treat?
Chemical removal of warts
Do warts reoccur?
Yes
How many vaccines are available for HPV?
2
How many polyomaviruses are known to exist?
10
What are important human polyomaviruses?
JC virus
BK virus
Merkel cell polyomavirus
Author
kyleannkelsey
ID
218476
Card Set
MIC 541-Exam 5-Virology 18
Description
MIC 541-Exam 5-Virology 18
Updated
2013-05-08T04:39:31Z
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