MIC 541-Exam 5-Virology 13

What general type of drug is Acyclovir?

Nucleoside analog
What is the most potent anti-herpetic medication?

Acyclovir
What is Famciclovir and Penciclovir?

Acyclic nucleoside analogs of guanosine
How do Famciclovir and Penciclovir compare to Acyclovir?
- Fam and Pen are less potent that Acyclovir
- Fam and Pen have better uptake and half-life
What drugs is an L-valyl ester of acyclovir?

Valacyclovir
What virus causes Chicken pox and shingles?

Varicella-Zoster virus
What type of virus is VZV?

Herpes virus
What hosts can VZV infect?

Humans only
How is VZV acquired?
- Respiratory/Airborne
- Aerosol/droplets
How long after VZV inoculation do lesions appear?

1-2 days
What is a characteristic lesion of Varicella virus?

Vesicles (chicken pox)
What are the treatments for VZV?
- Acyclovir
- Famciclovir
- interferon for systemic disease
What would you use to treat systemic VZV?

Interferon
What type of vaccine is available for VZV?

Live attenuated
What is disease is caused by zoster?

Shingles
What disease is caused by Varicella?

Chicken pox
What activate the zoster virus?

Stress
What cells are characteristic of Cytomegalovirus?

Giant cells with nuclear and cytoplasmic inclusions
How are Cytomegaloviruses transmitted?
- Saliva
- Breast milk
- Urine
- Semen
- Cervical secretions
Where doe Cytomegalovirus lay dormant?

Many tissues
What percent of adults are infected with Cytomegalovirus?

70-90%

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Card Set

MIC 541-Exam 5-Virology 13

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MIC 541-Exam 5-Virology 13

Updated

2013-05-08T04:36:16Z

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