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MIC 541-Exam 5-Virology 4
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Do DNA viruses need host machinery for replication?
Depends on the virus (Yes and No)
For enveloped viruses, where does assembly take place?
At the site of envelope acquisition (nucleus, golgi, etc.)
where does core assembly occur for DNA viruses?
In the Nucleus
Where does core assembly occur for RNA viruses?
The cytoplasm
What are the three ways viruses are released from the host cell:
Lytic
Exocytosis
Budding
Describe lytic release of viruses:
Critical mass is achieved by particle accumulation
Viral signal induce cell death and virion release
Describe exocytosis of virions from the host cell:
Via normal cellular pathways
When does viral maturation occur:
during or after budding /release
What is the signal for matureation of viruses?
Not known
Where do most DNA cell bud off?
The nucleus
What level of disease is caused by most viruses?
No disease at all
What are zoonoses?
Viruses that infect many animals
What are the most common manifestations of viruses:
Rashes
Fever
Muscle aches
Respiratory symptoms
Swollen lymph nodes
What type of infections are associated with RNA viruses?
Acute infection
What RNA viruses are not associated with acute infections?
Hep C
Retroviruses
What are the general body defenses to viruses?
interferon
Antibodies
Cytotoxic T cells
What type of immunity is usually acquired after contact with viruses?
Lifetime immunity
What is the most common viral infection course?
Rapid lytic course
How long can some viruses last in the host:
Chronic infections of years to a lifetime
What are the two types of persistent viral infections?
Chronic infections
Latent infections
What are chronic viral infections like?
Virus is detectable in tissue samples
multiplies at slow rates
mild or absent symptoms
What type of persistent viral infection is detectable in tissues, multiplies slowly and has mild or absent symptoms?
Chronic
Author
kyleannkelsey
ID
218389
Card Set
MIC 541-Exam 5-Virology 4
Description
MIC 541-Exam 5-Virology 4
Updated
2013-05-07T23:06:55Z
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