MIC 541-Exam 5-Virology 2

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What are the factors of susceptibility to viruses?
- Number of receptors
- ability of host to support virus
What type of measurement is Susceptibility?

Qualitative
What is the purpose of a capsid?

To stabilize and protect the genome
What type of environmental variations are capsids meant to protect against?
- Temp
- pH
- Chemical
What viral structure protects against Temperature, pH and chemical composition of the environment?

Capsid
What is another word for the viral Nucleocapsid?

Core
What forms the substructure of a viral particle?

The nucleocapsid
Describe an icosahedral viral shape:
- 520 triangular surfaces
- 2,3, and 5 fold axes of symmetry
What type of virus has a Helical formation, as described in class?

Tobacco mosaic viruses
What is an example of an ovoid virus?

Poxvirus
Describe a Helical formation of a virus?

Cylindrical
What is a variation of the icosahedrical viral shape?

Fullerene cone
Describe the composition of viral envelope:

Lipid bilayer with glycoproteins
Where does the viral envelope reside?

Outermost layer
What are the advantages of a viral envelope?

Protects against chemicals and enzymes
What are the disadvantages of a viral envelope?

Less stable in the environment
How do viruses acquire membranes?

By budding out of host
What host membranes are viral membranes derived from?
- Plasma membrane
- ER
- Golgi
- Nuclear membrane
Viral envelope proteins are post-translationally targeted to what?

The appropriate membrane
How (generally) do viruses replicate?
- Fusion and host cell entry
- Replication
- Assembly
- Release
- Maturation
What is the first step in Viral replication?
- Viral binding to host cell
- What is require for viral host cell binding?
- Specific host cell receptors-protein
- Lipids
- Carbohydrates

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kyleannkelsey

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Card Set

MIC 541-Exam 5-Virology 2

Description

MIC 541-Exam 5-Virology 2

Updated

2013-05-07T23:05:42Z

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