PTG 105-Exam 4-Neural 5

  1. Is dementia a specific disease?
  2. What is dementia?
    Any progressive loss of nerves in the CNS affecting memory and cognitive function
  3. Does having memory loss mean you have dementia?
    No dementia is in two or more areas of brain function
  4. What is the most common dementia disease in elderly?
    Alzheimer's disease
  5. How many people in the US have Alzheimer's?
    4.5 million
  6. What age does Alzheimer's usually begin?
    65 and up
  7. What proportion of people over 85 have Alzheimer's?
    nearly half
  8. What is a risk factor for Alzheimer's disease?
    Increasing age
  9. What area of the brain does Alzheimer's start with?
    The part that controls thought memory and language
  10. What is the rate of onset of Alzheimer's disease?
  11. What is the cure for Alzheimer's?
    No known cure
  12. What is the treatment for Alzheimer's?
    Aricept may slow progression of symptoms
  13. What does Alzheimer's brain look like?
    • large Suculi
    • Small Gyri
    • Large ventricle
    • Brain shrivels up
    • Plaques and neurofibrous tangles
  14. Where is brain shrinking especially severe in AD patients?
  15. What happens to the ventricles in AD?
    They grow larger
  16. What are the most indicative signs of AD?
    Plaques and Neurofibrous tangles
  17. What are Neurofibrous tangles and plaques?
    • Signs of Alzheimer's disease
    • Abnormal clumps and tangled bundles of nerves
  18. What is Parkinson's disease?
    Progressive loss of nerve cell function in brain that controls muscle movement
  19. What is the cause of Parkinson's disease?
    • Neurons that make dopamine die or stop working
    • Reduced dopamine
  20. What does dopamine usually do?
    Signaler for coordination of body movement
  21. What disease is marked by the death or lack of function of Brain neurons that secrete dopamine?
    Parkinson's disease
  22. When does Parkinson's usually begin?
    around age 60
  23. What are the signs of Parkinson's disease?
    • Trembling hands, arms, legs, jaw and face
    • Stiffness of arms, legs and trunk
    • Slow movement
    • Poor balance
  24. What is a characteristic symptom of Parkinson's disease?
    Pill-rolling tremor
  25. How is Parkinson's disease diagnosed?
    By symptoms, no specific test
  26. What is the treatment for Parkinson's disease?
    L-dopa for symptom relief
  27. What is the pathology of the brain in a parkinson's patient?
    • loss of pigment in substantia nigra
    • Intracytoplasmic inclusions called Lewy bodies
  28. If you examined a brain and saw intracytoplasmic inclusions and loss of pigment in the substantia nigra, what would your diagnosis be?
    Parkinson's disease
  29. What is vascular dementia?
    Multiple cortical infarcts from previous sustained strokes
  30. What is another name for Vascular Dementia?
    Mini infarct dementia
  31. What is the second most common form of dementia?
    Vascular dementia
  32. What is the best form of treatment for Vascular dementia?
    Prevention and early detection
  33. What are the risk factors for Vascular dementia?
    • Hypertension
    • Diabetes mellitus
    • Peripheral arterial disease
    • Smoking
  34. What is Huntington's disease?
    Autosomal dominant degeneration of basal ganglia causing dementia and involuntary movements
  35. What is an autosomal dominant disease that affects the basal ganglia andleads to dementia and involuntary movements?
    Huntington's disease
  36. What age is Huntington's disease most common?
  37. How is Huntington's disease aquired?
    Autosomal dominant inheritance
  38. What type of tretments are there for Huntington's disease?
    Only those for signs and symptoms not for prevention of further progression
  39. If one of your parents had huntington's disease, what are your chances of getting it?
  40. What does Chorea mean?
    Dance and refers to quick jerky movements
Card Set
PTG 105-Exam 4-Neural 5
PTG 105-Exam 4-Neural 5