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Parkinson's Disease

  1. carbidopa/levodopa
    Sinemet, sinemet CR, Parcopa ODT
  2. carbidopa/entacapone
    staleve
  3. benserazide/levodopa
    prolopa
  4. dopamine agents are used to treat which stages
    II - IV
  5. motor symptoms include
    • tremor
    • bradykinesia
    • postural instability
    • rigidity
  6. drugs that induce parkinsons
    • methyldopa
    • metoclopramide
    • neuroleptics
    • reserpine
  7. infections that induce PD
    • encephalitis
    • syphillis
  8. Toxins that induce PD
    • MPTP
    • CO poisoning
    • heavy metal poisoning
  9. neurologic disorders that induce PD
    • cerevrovascular disorders
    • lewy body dementia
  10. Stage I
    unilateral with minimal functional impairment
  11. Stage II
    Bilateral involvement but no postural abnormalitites
  12. Stage III
    bilateral with mild postural impairment (still able to function independently)
  13. Stage IV
    bilateral with postural instability; patient requires substantial assistance
  14. what are dopamine precursors effective for
    • bradykinesia
    • tremor
    • rigidity
    • (stages II - IV)
  15. which agents are used as adjuvants with sinemet
    dopamine agonists
  16. what is apomorphine used for
    rescue injection
  17. Bromocriptine
    • Parlodel
    • Dopamine agonist
  18. Pramipexole
    • Dopamine agonist
    • Mirapex
  19. ropinirole
    • Requip
    • dopamine agonist
  20. rotigotine
    • Neupro
    • dopamine agonist
  21. pergolide
    • permax
    • dopamine agonist
  22. benztropine
    • Cogentin
    • antichol
  23. trihexphenidyl
    • artane
    • antichol
  24. amantadine
    symmetrel
  25. what use does amantadine have
    improves bradykinesia, tremor, and rigidity in stage I-IV disease
  26. tolcapone is not used bc of what adverse effect
    hepatotoxicity
  27. entacopone
    comtan
  28. Selegiline
    • eldepryl
    • Zeplar
    • EMSAM
  29. selegiline comes in which dosage forms
    • tablet
    • ODT
    • transdermal patch
  30. uses for MAO-I
    adjunctive treatment in stage I-IV
  31. cautions for MAO-I use
    food-drug and drug-drug interactions with tyramine, meperidine, serotonergic drugs
  32. TEMPO
    rasagiline in early monotherapy
  33. ADAGIO
    Azilect given once daily
  34. DATATOP
    deprenyl and tocopherol antioxidative therapy of parkinsonism
  35. ELLDOPA
    earlier versus later levodopa
Author
alvo2234
ID
217718
Card Set
Parkinson's Disease
Description
Final Exam
Updated

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