Calcium Channel Blocker

• - Diltiazem is a slow calcium channel blocker similiar to verapamil.
• - Dilates coronary and peripheral arteries and arterioles, thus increasing circulation to the heart and reducing peripheral vascular resistance

• 1. Supraventricular tachydysrhythmias (AFIB, Atrial Flutter, PSVT refractory to adenosine)
• 2. Increase coronary artery perfusion in angina

• 1. Hypersensitivity
• 2. Sick Sinus Syndrome
• 3. 2nd or 3rd degree heart block
• 4. Systolic BP <90
• 5. Diastolic BP <60
• 6. Wide complex tachycardia
• 7. WPW

• 1. CHF
• 2. Conduction

0.25mg/kg IV over 2min, may repeat as needed with 0.35mg/kg followed by a drop of 5-10mg/hr. Not to exceed 15mg/hr over 24hrs

• Verapamil is a calcium channel blocker that slows AV conduction, suppresses reentry dysrhythmias such as PSVT, and slows ventricular responses to atrial tachydysrhythmias.
• - Also dilates coronary arteries and reduces myocardial oxygen demand

• 1. PSVT refractory to adenosine
• 2. Atrial Flutter
• 3. Atrial Fibrillation with rapid ventricular response

• 1. Severe hypotension
• 2. Cardiogenic shock
• 3. 2nd or 3rd degree heart block
• 4. CHF
• 5. Sinus Node Disease
• 6. Accessory AV pathways
• 7. WPW syndrome
• 8. Should not be given to pts taking beta blockers

2.5 - 5mg IV bolus over 2-3min, then 5 - 10mg after 15-30min to a max of 30mg in 30 min