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DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE
- Diazepam is a benzodiazepine sedative and skeletal muscle relaxant
- - reduces tremors
- - induces amnesia
- - reduces the incidence and recurrence of seizures
- - relaxes muscle spasms in injuries
- - produces amnesia for painful procedures (cardioversion)
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DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Indications
- - Major Motor Seizures
- - Status epilepticus
- - Premedication before cardioversion
- - Muscle tremors due to injury
- - Acute Anxiety
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DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Contraindications
- 1. shock
- 2. coma
- 3. acute alcoholism
- 4. depressed vital signs
- 5. obstretic patients
- 6. neonates
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DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Precautions
- 1. psychoses
- 2. depression
- 3. myasthenia gravis
- 4. COPD
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DIAZEPAM (VALIUM) / ANTI-ANXIETY, HYPNOTIC, ANTI-CONVULSANT, SEDATIVE Dosage/Route
- Seizures: 5-10mg IV/IM
- Acute Anxiety: 2-5mg IV/IM
- Premedication: 5-15mg IV
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FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST
Flumazenial is a benzodiazepine antagonist used to reverse the sedative, recall, and psychomotor effects of diazepam, midazolam, and other benzos
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FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Indications
Respiratory depression secondary to benzodiazepams
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FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Contraindications
- 1. Hypersensitivity to flumazenial or other benzos
- 2. Pts who take flumazenial for status epilepticus or seizures
- 3. Seizure-prone patients during labor & delivery
- 4. Tryicylic anti-depressant overdose
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FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Precautions
- 1. Hepatic impairment
- 2. Head Injury
- 3. Alcohol & drug dependency
- 4. Physical dependence on benzodiazepines
- 5. Elderly
- 6. Pregnancy & nursing mothers
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FLUMAZENIAL (ROMAZICON)/ BENZODIAZEPINE ANTAGONIST Dosage/Route
0.2mg IV over 30sec/min, up to 1mg
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MIDAZOLAM (VERSED) / SEDATIVE
- Midazolam is a short-acting benzodiazepine with:
- 1. CNS depressant
- 2. muscle relaxant
- 3. Anti-convulsant
- 4. Anterograde amnestic effects
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MIDAZOLAM (VERSED) / SEDATIVE Indications
To induce sedation before cardioversion or intubation
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MIDAZOLAM (VERSED) / SEDATIVE Contraindications
- 1. Hypersensitivity to benzos
- 2. Narrow angle glaucoma
- 3. Shock
- 4. Coma
- 5. Acute alcohol intoxication
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MIDAZOLAM (VERSED) / SEDATIVE Precautions
- 1. COPD
- 2. Renal impairment
- 3. CHF
- 4. elderly
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MIDAZOLAM (VERSED) / SEDATIVE Dosage/Route
1 - 2.5 mg slow IV; 0.07 - 0.08mg/kg IM
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