[PHARMACOLOGY] Antihyperlipidaemic

  1. classification of antihyperlipidaemic agents
    • HMG-Coa reductase inhibitor
    • Bile acid sequesterant
    • Niacin
    • Fibrates
    • Probucol
  2. example of HMG Coa reductase inhibitor
    • Fluvastatin
    • Lovastatin
    • Atorvastatin
    • Pravastatin
    • Simvastatin
  3. rate limiting enzyme in cholesterol synthesis
    HMG Coa reductase
  4. lipid lowering agent that blocks the initial step in cholesterol synthesis
    HMG Coa reductase inhibitor
  5. lipid lower agent which produce a lipid profile of elevated HDL and low LDL, VLDL and cholesterol
    HMG Coa reductase inihibitor
  6. lipid lowering agent with side effects of renal failure, rhabdomyolysis, myopathy and hepatic insufficiency
    HMG Coa reductase inhibitor
  7. upon the action of HMG Coa reductase, the HMG Coa will be converted to what substance?
  8. lipid lowering agent that lower absorption of fat soluble substances
    Bile acid sequesterant
  9. lipid lowering agent that disrupt the enterohepatic circulation of bile acids by combining with bile constituents and preventing reabsorption from the gut
    Bile acid sequesterant
  10. lipid lowering agent that also used to treat hyperthyroidism as an adjunct therapy
    • Bile acid sequesterant
    • by inhibiting the enterohepatic circulation, more L-thyroxine will be lost through defecation, thus lowering body thyroxine levels.
  11. lipid lowering agent which produce a lipid profile of elevated HDL, VLD and Triglycerides; and decreases cholesterol and LDL
    Bile acid sequesterant
  12. example of bile acid sequesterant
    • Cholestyramine
    • Colestipol
Card Set
[PHARMACOLOGY] Antihyperlipidaemic
Pharmacy Board Exam Reviewer