cytoprotective agent that will scavenge the acrolein byproduct that is renal/bladder toxic
Mesna sodium - Mesnex
boronic acid functional group 26 proteasome inhibitor
Bortezomib - Velcade
anti-mitotic spindle poison that stabilizes and promotes microtubule assembly
Docetaxel - Taxotere
aromatase inhibitor for treatment of estrogen dependent neoplasia
Anastrozole - Arimidex
treatment of extravasation due to leakage of aziridium based alkyation agent into tissue surrounding infusion site
sodium thiosulfate / ice packs
antidote to intention methotrexate high dosage treatment
levoleucovorin
CYP2D6 mediated competitive inhibition of metabolism
Tamoxifen/SSRI drug interaction
prodrug antineoplastic agent that requires CYP 450 activation to generate the nitrogen mustard alkylating species and the renal toxic acrolein byproduct
Cyclophosphamide - Neosar
inhibitor of protein tyrosine kinase in cancer treatment
Imatinib mesylate - Gleevec
alkylating agent used for bone marrow ablation therapy prior to bone marrow transplantation from a donor
Busulfan - Myleran
biotec product that is used to counter the severe mucositis inflammation of the mouth and intestinal tract from chemotherapy and radiation treatment
Palifermin - Kepivance
folic acid antagonist that is trapped once inside the cell following polyglutamate attachment
Pemetrexed - Alimta
responsible for the metabolism of all the protein tyrosine kinase inhibitors used to treat neoplasm
CYP3A4
leukopenia inducing antineoplastic agent that is used in sickle cell disease
Hydroxyurea - Hydrea
pyrimidine based antimetabolite drug
Fludribine - Fludara
Anti-emetic agent example of the type of drug everyone on chemotherapy/radiation should receive
Metoclopramide - Reglan
cytoprotective agent used to scavenge renal toxic platinum based excretion products
Amifostine - Ethyol
topoisomerase inhibitor
Etoposide - Toposar
cytoprotective agent used specifically to counter the cardiotoxicity of anthracyclines such as doxirubicin
Dexrazoxane - Savene
anti-neoplastic antibiotic with minimal bone marrow suppression properties
Bleomycin - Blenoxane
metoclopramide - Reglan
anti-emetic agent example of the type of drug everyone on chemo/radiation should receive
anastrozole - Arimidex
aromatase inhibitor for treatment of estrogen dependent neoplasia
palifermin - Kepivance
biotec product that is used to counter the severe mucositis inflammation of the mouth and intestinal tract from chemotherapy and radiation treatment
dexrazoxane - Savene
cytoprotective agent used specifically to counter the cardiotoxicity of anthracyclines such as doxirubicin
CYP3A4
responsible for the metabolism of all the protein tyrosine kinase inhibitors used to treat neoplasia
etoposide - Toposar
topoisomerase inhibitor
hydroxyurea - Hydrea
leukopenia inducing antineoplastic agent that is used in sickle cell disease
bortezomib - Velcade
boronic acid functional group 26 proteasome inhibitor
docetaxel - Taxotere
anti-mitotic spindle poison that stabilizes and promotes microtubule assembly
imatinib mesylate - Gleevec
inhibitor is protein tyrosine kinase in cancer treatment
amifostine - Ethyol
cytoprotective agent used to scavenge renal toxic platinum based excretion products
fludribine - Fludara
pyrimidine based antimetabolite drug
levoleucovorin
antidote to intentional methotrexate high dosage treatment
cyclophosphamide - Neosar
prodrug antineoplastic agent that requires CYP450 activation to generate the nitrogen mustard alkylating species and the renal toxic acrolein byproduct
bleomycin - Blenoxane
anti-neoplastic antibiotic with minimal bone marrow suppression properties
mesna sodium - Mesnex
cytoprotective agent that will scavenge the acrolein byproduct that is renal/bladder toxic
tamoxifen/SSRI drug interaction
CYP2D6 mediated competitive inhibition of metabolism
pemetrexed - Alimta
folic acid antagonist that is trapped once inside the cell following polyglutamate attachment
busulfan - Myleran
alkylating agent used for bone marrow ablation therapy prior to bone marrow transplantation from a donor
sodium thiosulfate / ice packs
treatment of extravasation due to leakage of aziridium based alkyation agent into tissue surrounding infusion site