PHA 327 - Exam 2 - Ointments 4

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What are the four areas for testing requirements of ointments?
- Microbial content
- Minimum Fill test
- Packaging storage and labeling
- Drug release
What are the Microbial content requirements for ointments?
- Meet acceptable microbial standards
- MUST contain antimicrobial preservatives
What does the Minimum fill test evaluate?

Net weight and Volume
What requirements are there for packaging/storage and labeling of ointments?
- Well closed containers
- Light needs
- Labeling of base used
What is the purpose of in Vitro drug release testing?

To ensure lot to lot uniformity
What testing is used to ensure lot to lot uniformity?

In Vitro release testing
What are the two most common containers fro ointments?
- ointment jars
- Tubes
What is a semisolid emulsion system with a creamy appearance?

Cream
What are creams?
- Semisolid emulsion systems with a creamy appearance
What is the purpose of a Cream?

For application to the skin or mucous membranes for protection, therapy and prophylactic purposes
What are the general classifications of Creams?
- Oil-in water creams
- Water in oil creams
What are oil in water creams used for?
- Foundation creams
- Hand creams
- shaving creams
What are water in oil creams used for
- cold creams
- emollient creams
What type of cream are foundation creams, hand creams and shaving creams?

oil in water creams
What type of cream is used to make cold creams and emollient creams?

Water in oil creams
What are the advantages of using O/W creams for drug delivery?
- Pleasing appearance
- good feeling
- non-greasy
- suitable for oozing wounds
What type of cream is good for drug delivery?

Oil in water
What type of cream is suitable for oozing wounds?

Oil in water
What is the composition of a normal ointment?

80% oil 20% water
What is the percentage ratio of a cream?

50% oil and 50% water
Are ointments or creams lighter in consistency?

Creams
Which is easier to spread over large areas of skin ointments or creams?

Creams
Which stays longer on the surface of the skin, ointments or creams?

Ointments
Which is absorbed into the skin more readily, ointments or creams?

Creams
Which is prescribed more for dry skin, ointments or creams?

Ointments

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kyleannkelsey

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PHA 327 - Exam 2 - Ointments 4

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PHA 327 - Exam 2 - Ointments 4

Updated

2013-04-21T04:22:30Z

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