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Propofol
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Propofol
Names / Class
Diprovan
Sedative
Hypnotic
Propofol
Mechanism of Action
Appears to inhibit GABA activity in the brain.
Ultra-short-acting non-barbituate, non-benzodiazopine hypnotic.
Propofol
Onset of Action
Peak Effects
Duration
Half-Life
9 - 36 seconds
3 - 5 minutes
6 - 10 minutes
5 - 12 hours
Propofol
Indications
Induction and maintenance of sedation
Propofol
Contraindications
Known hypersensitivity to the drug or to egg or soybean products.
Increased cranial pressure
Propofol
Precautions
Potent sedative:
use only with adequate monitoring
have resuscitative equipment available
Propofol
Side Effects
Pain on induction
Hypotension
Apnea
HA
Nausea / Vomiting
Propofol
Adult Dose
2 mg/kg IV for induction/intubation
followed by 25 - 75 mcg/kg/minute as needed
Procedural sedation requires less: 0.5 - 1.0 mcg/kg/minute
Propofol
Pedi Dose
1 mg/kg IV
Propofol
Max Dose
Unknown
Propofol
Routes / How Supplied
IV
PO
Unknown
Author
Ritameeker
ID
213277
Card Set
Propofol
Description
Propofol
Updated
2013-04-13T22:46:01Z
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