Respiratory System

  1. Discuss the Nervous System and its relationship to alveolar ventilation.
    It automatically adjusts the rate of alveolar ventilation almost exactly to the body's demands. t
  2. What effect does the nervous system have on arterial PO2 and PCO2?
    They are hardly modified even with moderate to intense exercise or other respiratory distress
  3. What is the Repiratory center composed of?
    Several groups of neurons located bilaterally in the brain stem of the CNS specifically at the medulla oblongata and pons
  4. List location of Dorsal Resp Group and function
    • -Dorsal portion of medulla oblongata.
    • -Mainly inspiration
  5. List location of Ventral Resp Group and function
    • -Ventrolateral portion of medulla
    • -Inspiration or expiration depending on the nerves stimulated
  6. List location of Pneumotaxic center and function
    • -Dorsally located in the pons
    • -rate and pattern of breathing
  7. What is the most important role the dorsal resp group plays
    • -controlling respiration
    • -it receives information from the chemoreceptors and other receptors in the lungs that help in the control
  8. What is a ramp signal?
    The signal transmitted to the primary inspiratory muscles (diaphragm and external intercostals)
  9. Discuss the process of transmitting a ramp signal.
    -Starts from 0 and continues with a steady increase for about 2 seconds.

    -Stops for 3 sec and starts again thus causing a steady increase in the pulmonary volume  during inspiration instead of inspiratory gasps
  10. The duration of expiration is determined by what?
    The duration of inspiration
  11. What does the pneumotaxic center limit?
    It limits the duration of inspiration and increases the resp rate
  12. What is the result of strong signals from the pneumotaxic center?
    Stong signals reduce the time of inspiration while weak signals increase it.
  13. What is the ventral group mostly involved in?
    In increased levels of ventilation
  14. What is the ultimate goal of resp?
    To maintain proper H+, O2 and CO2 in tissues, something achieved by the resp activity
  15. What causes "DIRECT" stimulation of the resp center?
    • An increase in H+ and CO2.
    • -Causes an increase of the inspiratory and expiratory signals
    • -
  16. Does O2 have a "direct" effect on the resp center?
    • -No.
    • -It acts through the peripheral chemoreceptors located in the carotid and aortic bodies
  17. What occurs after fresh O2 gets to the alveoli?
    The next step is its diffusion into the pulmonary blood and CO2 in the opposite direction
  18. What is the net diffusion of a gas?
    The net diffusion of a gas in one direction is a direct effect of its concentration gradient and its pressure against a surface is caused by the constant impact of kinectically moving molecuels against that surface.
  19. What is the rate of diffuion of O2, CO2 and N2?
    The rate of diffusion of each of these gases is directly proportional to the pressure caused by this gas alone, known as the partial press of the gas
  20. What is the partial pressure of N2?
    79% or 600mm/Hg at sea level
  21. What is the partial pressure of O2?
    21% or 160 mm/Hg at sea level
  22. What is total pressure?
    The sum of all partial pressures
  23. What results from gases dissolved in H2) or the body tissues?
    They exert pressure because the dissolved molecules are moving randomly and have kinetic energy.

    -When they encounter a surface like the membrane of a cell the result is the same
  24. What determines the pressure of a gas in a solution?
    Its concentration and the solubility coefficeint of the gas
  25. What is Henry's Law?
    • Pressure = [Dissolved Gas]
    •                 --------------------
    •                Solubility Coefficient
  26. What is the solubility coefficient at body temp of O2, CO2, CO, N2 and He2?
    • O2= 0.024
    • CO2= 0.57
    • CO = 0.018
    • N2= 0.012
    • He= 0.008
  27. What effect does the partial pressure of each gas have on a solution?
    It tends to force molecules of that gas into the solution, first in the alveolar membrane and then in the blood of the alveolar capillaries
  28. What is the rate at which each gas escapes a medium?
    The rate at which they escape from one medium to another is directly proportional to their partial pressure in the blood

    -the net diffusion is determined by the diff b/w the two partial press.
  29. What causes the net diffusion of gases through fluids?
    The pressure difference
  30. What is the pressure difference for diffusion?
    The gas press difference b/w two areas
  31. Explain why alveolar air doesn't have the same composition of the atmospheric air.
    • b/c alveolar air is only partially replaced with each breath
    • - O2 is going to the blood
    • -CO2 is coming from the blood 
  32. What happens to dry atmospheric air that enters the resp pathways?
    It is immediately humidified even before reaching the alveoli
  33. What is tidal volume and its measurement in an average adult male?
    • -500 ml
    • -amt of air inhaled or exhaled w/ each breath under resting conditions
  34. What is inspiratory reserve volume and its measurement in an average adult male?
    • -3100 ml
    • -amt of air that can be forcefully inhaled after a normal tidal volume inhalation
  35. What is expiratory reserve volume and its measurement in an average adult male?
    • -1200 ml
    • -amt of air that can be forcefull exhaled after a normal tidal volume exhalation
  36. What is residual volume and its measurement in an average adult male?
    • -1200 ml
    • -amt of air remaining in the lungs after a forced exhalation
  37. What is total lung capacity (TLC) and its measurement in an average adult male?
    • -6000 ml
    • -max amt of air contained in lungs after a max inspiratory effort
    • -TLC = TV+IRV+ERV+RV
  38. What is vital capacity (VC) and its measurement in an average adult male?
    • -4800 ml
    • -max amt of air that can be expired after a max inpiratory effort (should be 80% TLC)
    • -VC=TV+IRV+ERV
  39. What is inspiratory capacity and its measurement in an average adult male?
    • -3600 ml
    • -max amt of air that can be inspired after a normal expiration
    • -IC= TV+IRV
  40. What is functional residual capacity (FRC) and its measurement in an average adult male?
    • -2400 ml
    • -volume of air remaining in the lungs after a normal tidal volume expiration
    • -FRC= ERV+RV
Card Set
Respiratory System
Respiratory System