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What would you expect to see in a joint with Osteoarthritis?
- thinned cartilage
- Bone spurs
- Carilage fragments
- Inflammed synovium
- Tight thickened capsule
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What is Rheumatoid arthritis?
Chronic inflammatory disease that attacks joints
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What group is most affected by Rheumatoid arthritis?
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What other organs can be affected by Rheumatoid arthritis?
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What is the etiology of Rheumatoid arthritis?
Autoimmune
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What changes occur in joints with Rheumatoid arthritis?
- Inflammation of the synovium
- Desruction of articular cartilage
- Gradual fibrosis
- Impairment
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What joints are usually involved in Rheumatoid arthrirtis?
- Small joints of hands and feet
- Later: wrist, elbow, ankle and knees
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How long does Rheumatoid arthritis usually last?
Lifetime, progressive disease
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What are the symptoms of Rheumatoid arthritis?
Painful, swollen and warm joints often in the morning
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What is Pannus formation?
Inflammation of the synovium containing masses of inflammatory cells
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What is the term for inflammed synovium that contains masses of inflammatory cells/
Pannus
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What is gout?
Accumulation of excessive amounts of uric acid due to abnormal metabolism
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What is the term for accumulation of excessive amounts of uric acid due to abnormal metabolism?
Gout
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What happens to excess uric acid in gout?
It is deposited in soft tissue, leading to joint pain and arthritis
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What group is susceptible to gout?
Mostly men (90%) over the age of 30 years
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What is the most common spot for gout?
big toe (90%)
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What are common areas for gout to affect patients?
- Big toe (90%)
- Ankle
- Heel
- Fingers
- Wrist
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Untreated gout after many occurances can cause what?
Joint damage
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Describe the histology of Gouty tophus?
Aggregates of urate surrounded by inflammatory cells
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Aggregates of urate surrounded by inflammatory cells is called what?
Gouty tophus
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What is another name for Infectious arthritis?
acute suppurtive arthritis
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What is another term for acute suppurative arthritis?
infectous arthritis
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What are the common causes of Infectous arthritis?
- pyogenic bacteria gonococci
- staphylococci
- streptococci
- In sickle cell patients = Salmonella
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How many joints at once will be affected by Infectous arthritis usually?
Monoarticular = one joint
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What are some symptoms of Infectous arthritis?
local heat, pain, welling, tenderness, fever and pus on aspiration
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What disease is indicated form a patient presenting with local heat, swelling and joint pain with tenderness and pus upon aspiration?
Infectous Arthritis
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What might you see in a slide of the pus from a person with Infectous arthritis?
- Gram negative intracellular diplococci
- =Gonorrhea
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