Acts as physiologic calcium channel blocker and block the, CNS depressant and anti-convulsant neuromuscular transmission. Depresses the function of smooth, skeletal, and cardiac muscles
Indications
- Refractory ventricular fibrillation
- Pulse-less ventricular tachycardia
- Torsade de pointes
- Eclamptic seizure
- AMI
Contraindications
- Hypocalcemia
- Hypertension
- Heartblock
- Myocardial Damage
- Shock
Precautions and Side Effects
- ALOC
- Hypotension
- Heartblock
- Hypocalcemia
Dosage (Adult)
V-FIB / V-TACH (pulse-less) - 1-2 grams IV over 1-2 mins
Torsades de pointes - 1-2 grams IV followed by 0.5-1.0 g/hour