-
Adrenaline
- Adrenergic agonist
- α2 >=α1 >β1 =β2
-
Noradrenaline
- Adrenergic agonist
- a1 > a2 = b1 >> b2
-
Phenylbutazone
- Vet NSAID
- Scavenges free radicals
- eliminated principally by drug metabolism
-
Flunixin
- Vet NSAID
- Anti-bradykinin effects
- Inhibition of NFkB
-
Carprofen
- Vet NSAID
- Inhibition of cytokine release
- Inhibition of NFkB
- Human: COX-1 > COX-2
- Horse: COX-1 = COX-2
- Dog/Cat: COX-1 < COX-2
-
Loperamide
kept out of the brain by P-glycoprotein
-
Coumarin
- Analogue= warfarin, 4-hydroxycoumarin, Dicoumarol
- Anti-coagulant rodenticide
-
Etamiphylline
- Methylxanthines
- Commonly used cardiac & respiratory stimulant in veterinary practice
-
N-acetyl cysteine
Replenishes GSH in acute liver failure
-
Purine
Includes: xanthine, theobromine, uric acid and caffeine
-
Theobromine
- Purine
- Methylxanthine
- Toxic to dogs (some cats)
- In chocolate
-
Theophylline
- Methylxanthines
- Bronchodilator/respiratory stimulant
-
Xanthine
- Uric acid is metabolite
- Methylxanthines: anatagonists of adenosine receptors, inhibitors of phosphodiesterase, activation of ryanodine receptors [positive ionotropic effect]
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