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Narcan
Names / Class
Naloxone
Narcotic Antagonist
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Narcan
Mechanism of Action
- Binds to opiate receptors in the brain to block narcotics from binding to the receptors, blocking the narcotics effects.
- Displaces narcotic molecules from opiate receptors.
- Can reverse respiratory depression associated with narcotic overdose.
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Narcan
Onset of Action
Peak Effects
Duration
Half-Life
- <2 minutes
- <2 minutes
- 20 - 120 minutes
- 60 - 90 minutes
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Narcan
Indications
- Narcotic overdoses including:
- morphine, hydromorphone (Dilaudid), Fentanyl, Demeral, Methadone, Heroin, Hydrocodone, Oxycodone (Percodan, Percocet)
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Narcan
Contraindications
Hypersensitivity to the medication
-
Narcan
Precautions
- May cause withdrawel effects in Pts dependant on narcotics.
- Short acting - should be augmented every 5 minutes.
-
Narcan
Side Effects
- Rarely any side effects:
- hypotension
- HTN
- Ventricular arrhythmias
- Nausea / Vomiting
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Narcan
Adult Dose
1 - 2 mg IV/IO
-
Narcan
Pedi Dose
- <5 years old: 0.1 mg/kg
- >5 years old: 1 - 2 mg
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Narcan
Routes / How Supplied
- IV
- IO
- IM
- ET (2 - 2.5 x dose)
- Intranasal
- Small volume nebulizer
Vial?
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