MJC Micro

• *Gram + rod
• *Digests Sebum
• *Attracts Neutrophils
• *Neutrophil digestive enzymes cause lesions, "pus pockets"
• *Most common skin disease in humans

• TREATMENTS
• *Bonzoyl peroxide-dries plugged folicles, kills microbes
• *Tetracycline (antibiotic)
• *Accutane-inhibits sebum formation

• Peeling Crusty Skin
• Contagious

• *Associated with a number of diseases, including impetigo
• *Enzymes are virulence factors
• *Most treated pathogen

*A positive coagulase test is a primary method of identifying staphyloccus aureus

• Streptococcus pyogenes (Group A Strep)
• *Tissue digesting enzymes
• *Rapidly spreading cellulitis may lead to a loss of limb
• *Disease starts as localized infection, pain in area, flu-like symptoms
• *Invasive and Spreading
• *may lead to toxic shock (drop in blood pressure)
• *30-70% mortality rate
• *surgical removal

• *Disease of skin and nerves
• *change of pigmentation, loss sensation
• *slow progressing
• *transmits poorly
• *droplet or skin contact
• *Slow growth, prefers cool areas of body
• *acid fast bacterium
• **Armadillas harbor bacteria

• Measles virus(Rubeola)
• Rubella Virus (german measles)
• Roseola (human herpesvirus-6)
• Fifth Disease (human parvovirus B19)

• Viral infection through aerosl droplet: One of the most communicable viruses
• *local infection lymph nodes (of the neck)
• *lymphocyte associated viremia, fever, malaise
• *Spread throughout the body
• *shed in respiratory tract secretions, Kopliks spots & skin rash
• *recovery, life long immunity
• *Measels is the leasing cause of vaccine preventable death among children

***The primary reason for ongoing high childhhod deaths is the failure to deliver at least one of the measles vaccine.

• *Viral infection through aerosol droplet; systemic infection
• *Mild rash
• *serious to the fetus when contracted in the first trimester of pregnancy
• *Congenital Rubella Syndrome
• *small birth weight, blindness, hearing loss, mental retardation
• *infection lasts for months to years iin the newborn
• MMR vaccine highly effective

• Smallpox (Human Pox Virus)
• Cold Sores (Human simplex 1 & 2)
• Chickenpox (Human herpesvirus-3)

• Common Virus; decreasing disease in the USA due to effective childhood vaccine.
• *Benign disease with life long immunity
• *May reemerge as shingles (skin lession):cause: stress, xrays, drugs

• *local infection in the lymph nodes
• *lymphocyte associated viremia, fever, malaise
• *spread throughout the body
• *shed is respiratoy tract secretions and skin vessicles (blisters of clear fluid)
• *life long immunity

• *Very infectious viral disease epidemic)
• *a Jennerian vaccine (named for Edward Jenner, 1796)
• *This virus has been preserved in government labs by agreement, at CDC in Atlanta, and in Russia
• *Considered a bioterrorism agent

• Mostly a benign viral infection
• *nearly everyone is infected
• *different virus types
• -plantar warts
• flat warts
• genital warts

• Fungal Infection (mycosis)
• -dermatophyte
• Conditions name-tinea
• scalp-capitas
• beard-barbae
• body-corporis
• groin-cruris
• foot- pedis
• hand -poris
• nail- unguium

• Herpesvirus Keratitis (Human simplex 1)
• Chlamydial infection of the eye
• Chlamydia trachomatis causes trachoma and can lead to blindness

**Both are spread by contact with infected secretions

• CNS: brain and spinal cord
• PNS: peripheral nerves
• -Cells are called neurons
• -No normal flora

• -Skull and Vertebrae
• -Microglial cells and macrophages
• -Restricted entry into brain (blood-brain barrier) for:
• microorganisms, medications, including most antibiotics, immune system

Can be caused by both bacteria, viruses & parasites

inflammation of the meninge= membranes surrounding the brain and spinal cord

Inflammation of the brain

• Arbo (arthropod-borne) viruses
• -Ex. West Nile Virus
• Rabies
• Poliomyelitis
• Neurotoxins
• Tetanus