-
because it is a short rod, it can be known as a coccobacillus
Bordatella pertussis
-
an airborne organism
nonmotile
grows well in and on the mucous membranes of the upper respiratory tract
Bordatella pertussis
-
easily transmitted from person to person by droplet spray and nasal secretions
Bordatella pertussis
-
produces an exotoxin called "pertussis toxin"
this causes most of the symptoms
Bordatella pertussis
-
affects mainly young children
Bordatella pertussis
-
the cilia of the respiratory tract are destroyed by the toxin excreted by this bacterium
Bordatella pertussis
-
there is no way for the excess mucous being produced to be removed from the tract except by intense coughing
pertussis
-
-
-
the fits of coughing are prolonged and uncontrollable
paroxysm
pertussis
-
the coughing fits are followed by a huge gasp of air that generates the characteristic "whoop" sound from which the disease got it's name
whooping cough
-
these may also be know as coccobacillus
nonmotile
this genus requires certain components of the blood for survival
Haemophilus sp.
-
Haemophilus means:
blood loving
-
components of Haemophilus sp.
X-factor
V-factor - it is a nucleotide
-
has a polysaccaride capsule that increases its virulence greatly
Haemophilus influenzae
-
was once thought to be the sole cause of influenza
Haemophilus influenzae
-
known most often be a secondary infection of influenza
Haemophilus influenzae
-
known most often be a secondary infection of influenza
bacterial influenza
Haemophilus influenzae
-
often causes an acute epiglottitis that can cause asphyxia
Haemophilus influenzae
-
before a vaccine was developed, it often caused meningitis in infants
Haemophilus influenzae
-
a common cause of acute conjuctivitis or "epidemic pinkeye" in school-aged children
Haemophilus influenzae
-
acute conjuctivitis or "epidemic pinkeye" in school-aged children was once attributed to a species
Haemophilus aegyptius
-
acute conjuctivitis or "epidemic pinkeye" in school-aged children is now known to be caused by a separate strain of
H. influenzae
-
causes the STD Chancroid
Haemophilus ducreyi
-
causes the formation of one or more tender raised lesions or papules on the genitals
Haemophilus ducreyi
STD Chancroid
-
the tender raised lesions or papules on the genitals are similar to the chancre of _______ but is soft
syphilis
STD Chancroid
-
the tender raised lesions or papules on the genitals then develop into
painful open lesions
STD Chancroid
-
infects the regional lymph nodes causing a painful swelling
-
may be known as a coccobacillus
nonmotile
a zoonosis that rarely affects humans
Yersinia pestis
-
causes the disease "the plague"
Yersinia pestis
-
spread by the bites of infected fleas
usually the rat flea
Yersinia pestis
-
as the flea bites a new host, it regurgitates infectious material from its intestinal system into the bite wound; the bacteria then move through the lymph system to the lymph nodes and cause a painful infection and swelling
Yersinia pestis
-
the Yersinia pestis infection and swelling of a lymph node is called a ________ therefore the name _____ _____
1. Bubo
2. Bubonic plague
-
if the infection moves into the bloodstream, it will commonly infect the lungs; this causes the condition of
pneumonic plague
-
a disease with high fatality rates
can now spread the organism via droplet spray
this form of the disease is considered to be an effective biological weapon
pneumonic plague
Yersinia pestis
-
known as a coccobacillus
nonmotile
a zoonosis that is more likely to affect humans than Yersinia
Francisella tularensis
-
not uncommon in hunters or trappers after skinning wild animals
especially rabbits
Francisella tularensis
-
it causes the disease tularemia or rabbit fever
Francisella tularensis
-
Francisella tularensis is spread in several ways a (1 of 5)
inolculation of the skin or mucous membrane with blood or tissue of an infected animal
-
Francisella tularensis is spread in several ways a (2 of 5)
from the bite of an infected deer fly or tick
-
Francisella tularensis is spread in several ways a (3 of 5)
handling or eating insufficiently cooked meat
-
Francisella tularensis is spread in several ways a (4 of 5)
drinking contaminated water
-
Francisella tularensis is spread in several ways a (5 of 5)
handling contaminated pelts or paws of infected animals
-
Francisella tularensis will cause the following symptoms (1 of 5)
an ulcer at the site of infection
-
Francisella tularensis will cause the following symptoms (2 of 5)
swelling and tenderness of the surrounding lymph nodes
-
Francisella tularensis will cause the following symptoms (3 of 5)
high fever
-
Francisella tularensis will cause the following symptoms (4 of 5)
shaking chills
-
Francisella tularensis will cause the following symptoms (5 of 5)
debilitating headaches
-
Francisella tularensis rarely causes death but...
the fever may last for more than a month
those who recover are often incapacitated for several weeks or even months
-
Short, aerobic, gram-negative rods
Bordatella pertussis
Haemophilus sp.
Yersinia pestis
Francisella tularensis
-
Spore-forming bacilli
Bacillus sp.
Clostridium sp.
-
Aerobic Spore-forming bacilli
Bacillus
-
Anaerobic Spore-forming bacilli
Clostridium
-
the causitive agent of anthrax
Bacillus anthracis
-
gram-positive organism
nonmotile
primarily a zoonosis of herbivorous animals
Bacillus anthracis
-
the most common manifestation of Bacillus anthracis is as
cutaneous anthrax
-
usually acquired via injured skin or mucous membranes
cutaneous anthrax
Bacillus anthracis
-
spores are inoculated from the soil, contaminated animal or carcass, etc.
cutaneous anthrax
Bacillus anthracis
-
the spores germinate and the vegetative cells multiply
cutaneous anthrax
Bacillus anthracis
-
a gelatinous edema develop at the site of infection
cutaneous anthrax
Bacillus anthracis
-
a gelatinous edema develops into papules
cutaneous anthrax
Bacillus anthracis
-
papules change into vesicles
cutaneous anthrax
Bacillus anthracis
-
vesicles change into pustules
cutaneous anthrax
Bacillus anthracis
-
pustules change into necrotic ulcer
cutaneous anthrax
Bacillus anthracis
-
from the necrotic ulcer, it then enters the blood stream and causes septicemia
cutaneous anthrax
Bacillus anthracis
-
septicemia will likely lead to death
cutaneous anthrax
Bacillus anthracis
-
can manifest as pulmonary or respiratory anthrax
cutaneous anthrax
Bacillus anthracis
-
________ or _________ _________ is also known as Wool-Sorters disease
pulmonary/respiratory anthrax
Bacillus antracis
-
transmitted via dust from infected animals or their hides
pulmonary/respiratory anthrax
Bacillus antracis
-
once inhaled, the spores germinate quickly and the bacilli quickly enter the bloodstream; this causes septicemia and leads to death
pulmonary/respiratory anthrax
Bacillus antracis
-
extremely rare manifestation of Bacillus antracis
gastrointestinal or typhoidal anthrax
-
affects the intestinal tract
transmitted by eating the meat of infected animals
gastrointestinal or typhoidal anthrax
Bacillus antracis
-
gram-positive organism
motile with a single flagellum
Clostridium tetani
-
Clostridium tetani endospore formation
occurs at the end of the bacillus
it causes the classic (chicken) drumstick appearance
-
the exotoxin of this bacterium that causes disease rather than the organism itself
Clostridium tetani
-
Clostridium tetani exotoxin
tetanospasmin
-
one of the most potent toxins known to man
tetanospasmin
-
portal of entry of Clostridium tetani
the spores enter through a deep puncture wound
-
modes of transmission of Clostridium tetani
this is infectious but not communicable
a person can be infected by the organism but is not able to transmit the disease to another
-
modes of transmission of Clostridium tetani
it is only transmitted through contaminated soil carrying the spores into a deep wound
the soil may live for years in soil or contaminated feces
-
the disease caused by the exotoxin tetanus
Clostridium tetani
-
once the spores have entered the wound they must wait for the wound to become anaerobic before they germinate
Clostridium tetani
-
the organism does not spread but produces the exotoxin that diffuses into surrounding tissue
Clostridium tetani
-
this exotoxin is then picked up by the blood and distributed systemically causing severe muscle spasms
tetanus
Clostridium tetani
-
one of the first areas to be affected is the massiter muscle
causing it to become paralyzed
therefore the common name for the disease
lock jaw
tetanus
Clostridium tetani
-
eventually other muscles are affected and the entire body may be paralyzed
tetanus
Clostridium tetani
-
spasms of the facial muscles cause the appearance of a fixed smile and raised eyebrows
sardonic grin
tetanus
Clostridium tetani
-
minor noises, the bed being jarred, or simply a draft may trigger spasms
tetanus
Clostridium tetani
-
rigid chest muscles and throat spasms may lead to:(2)
oxygen deprivation
fatal suffocation
Clostridium tetani exotoxin
-
immunization can be accomplished woth the DPT vaccine
the "T" stands for tetanus toxoid
it lasts for up to 10 years
Clostridium tetani exotoxin
-
gram-positive organism
motile with a single flagellum
endospore formation occurs
Clostridium perfringens
-
the organisms are highly invasive because of the presence of a variety of exotoxins and enzymes that allow it to spread readily
Clostridium perfringens
-
there are as many as 12 different exotoxins produced by this organism
Clostridium perfringens
-
the exotoxins of this bacterium cause disease rather than the organism itself
mainly the alpha toxin
Clostridium perfringens
-
Clostridium perfringens portal of entry
deep puncture wound
-
Clostridium perfringens mode of transmission (2):
transmitted by contaminated soil carrying the spores into a deep wound
transmitted via the fecal-oral route through contaminated food
-
Clostridium perfringens pathogenicity (3)
- 1.gas gangrene
- 2. tissue gas
- 3. food intoxication
-
the death of otherwise normal tissue around a deep puncture wound
gas gangrene
-
it's distributed by bubbles of H+ & CO2 gas
produced by the organism
gas gangrene
-
spreads rapidly and will readily cause death
gas gangrene
-
gas gangrene can only be treated by (3):
- 1. surgical excision
- 2. amputation
- 3. hyperbaric oxygen therapy
-
same condition as gas gangrene except occurs in only a non-living host
tissue gas
-
often spread via contaminated embalming instraments carrying spores
tissue gas
-
this organism may also cause a severe gastroenteritis
food intoxication
-
produced by the presence of spores in food that is kept warm (such as a buffet) which allows the spores to germinate
food intoxication
-
an enterotoxin is produced and ingested to cause the disease
food intoxication
-
gram positive organism
motile with a single flagellum
endospore formation occurs
it is the exotoxins of this bacterium that causes disease rather than the organism itself; specifically neurotoxins
Clostridium botulinum
-
this toxin is the most poisonous natural substance known to man
neurotoxins
Clostridium botulinum
-
most often occurs in home-canned foods
these are often not heated enough to kill the spores
Clostridium botulinum
-
after canning the spores germinate and vegetative cells form
release the exotoxin
Clostridium botulinum
-
the exotoxin causes a flaccid paralysis in the host
Clostridium botulinum
-
the neurotoxin attaches to the nerve at the point of contact with the muscle it controls causing paralysis
Clostridium botulinum
-
death is most often by asphixiation
the diaphragm and the intercostal muscles become flaccis and cease to contract
Clostridium botulinum
-
could be prevented by simply heating the canned foods well enough after opening to inactivate the toxin
Clostridium botulinum
-
-
X factor
a nucleotide
Haemophilus sp.
-
Usually acquired via injured skin or mucous membranes.
Bacillus anthtacis
-
Transmitted via dust from infected animals or their hides.
Bacillus anthtacis
-
Transmitted by eating the meat of infected animals.
Bacillus anthtacis
-
Those who recover are often incapacitated for several weeks or even months.
Francisella tularensis
-
The spores may live for years in soil or contaminated feces.
Clostridium tetani
-
The most poisonous natural substance known to man.
Clostridium botulinum
-
The exotoxin causes most of the symptoms.
"pertussis toxin"
-
The diaphragm and intercostal muscles become flaccid and cease to contract.
Clostridium botulinum
-
The death of otherwise normal tissue around a deep puncture wound.
gas gangrene
-
The condition is infectious but not communicable.
Clostridium tetani
-
The cilia of the respiratory system are destroyed by the toxin.
Bordatella pertussis
-
Spread via contaminated embalming instruments.
tissue gas
-
Spread by the bite of an infected flea.
Yersinia pestis
-
Shaking chills
Francisella tularensis
-
Requires certain components of the blood for survival.
Haemophilus sp.
-
Regurgitates infectious material from its intestinal system into the bite wound.
Yersinia pestis
-
Rat fleas
Yersinia pestis
-
Produces food intoxication by the presence of spores in food that is kept warm on a buffet.
Clostridium perfringens
-
Produces an exotoxin called 'pertussis toxin".
Bordatella pertussis
-
Primarily a zoonosis of herbivorous animals.
Bacillus anthracis
-
Paroxysm
Bordatella pertussis
-
Organisms are highly invasive because of a variety of exotoxins and enzymes.
Clostridium perfringens
-
One or more tender, raised lesions or papules on the genitals.
Chancroid
-
One form of the disease is considered to be an effective biological weapon(2 answers)
pneumonic plague
Yersinia pestis
-
Once thought to be the sole cause of influenza.
Haemophilus influenzae
-
Occurs in home-canned foods.
Clostridium botulinum
-
Must wait for the wound to become anaerobic before spores can germinate
Clostridium tetani
-
Moves through the lymph system to the lymph nodes causing a painful swelling and infection.
Yersinia pestis
-
Most often a secondary infection of influenza.
Haemophilus influenzae
-
Most common manifestation is a cutaneous form.
Bacillus anthracis
-
Minor noises, jarring the bed, or a draft in the room may trigger muscle spasms.
Clostridium tetani
-
May die due to oxygen deprivation and fatal suffocation
Clostridium tetani
-
May be transmitted via the fecal-oral route into contaminated food.
Clostridium perfringens
-
Makes one of the most potent toxins known.
Clostridium tetani
tetanospasmin
-
Hyperbaric oxygen therapy.
Clostridium perfringens
-
Has a "drumstick" appearance.
endospore of Clostridium tetani
-
Grows well on the mucous membrane of the upper respiratory tract.
Bordatella pertussis
-
Fits of coughing followed by a huge gasp of air.
"whooping cough"
paroxysm
Bordatella pertussis
-
Fever may last for more than a month
Francisella tularensis
-
Distinguished by bubbles of hydrogen and carbon dioxide gases.
Clostridium perfringens
-
Death is most often by asphyxiation.
Clostridium botulinum
-
Common in hunters and trappers after skinning wild animals.
Francisella tularensis
-
Causes the look of a fixed smile and raised eyebrows.
Clostridium tetani
-
Causes severe muscle spasms.
Clostridium tetani
-
Causes a soft chancre.
Haemophilus ducreyi
-
Causes a flaccid paralysis.
Clostridium botulinum
-
Caused specifically by neurotoxins.
Clostridium botulinum
-
Can only be treated by surgical excision, amputation or oxygen therapy.
Clostridium perfringens
-
infection and swelling of a lymph node by Yersinia pestis
Bubo
-
Before a vaccine was developed, it often caused meningitis in infants.
Haemophilus influenzae
-
An STD that infects the regional lymph nodes.
Chancroid
Haemophilus ducreyi
-
An STD
Chancroid
Haemophilus ducreyi
-
Alpha toxin
exotoxin of Clostridium perfringens
-
Affects the masseter muscle.
Clostridium tetani
-
Affects mainly young children.
pertussis toxin
Bordatella pertussis
-
A zoonosis that rarely affects humans.
Yersinia pestis
-
A zoonosis that is more likely to affect humans.
Francisella tularensis
-
A polysaccharide capsule increases its virulence.
Haemophilus influenzae
-
A disease with high fatality rates.
Yersinia pestis
-
"Sardonic grin"
Clostridium tetani
-
"lntense cough"
pertussis
-
"Blood-loving"
Haemophilus
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