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WBC's
normal: 5-10k
elevated: leukocytosis, inflammation or infection, use of steroids, stress
decreased: immunocompromised
-
Neutrophils (PMN's)
Granulocyte (type of phagocyte)
Body's main defense
Nl: 45-74%
Mature segmented or bands (immature)
Bands: 0-4% nl, a "shift to the left" is 10-12% bands or > 80% bands means bacterial infection/sepsis
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Lymphocytes
T-cells, B-cells
- function to express antigens, acquired immunity
Increased: mono, viral or bacterial infections, leukemias, multiple myeloma
Decreased: AIDS, lupus, renal fx, sepsis
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Monocytes
enter tissues to become macrophages, produce antibodies to activate lymphocytes
Increased in chronic inflammation, parasitic infection, TB, viral infection
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Eosinophils
in response to allergies
Increased: allergic reaction, asthma, Hodgkin's disease
-
Basophils
Promote inflammatory response, contain histamine.
-
Critical Hemoglobin parameters
Hgb <5 TRANSFUSE
Hbg < 10, anemia w/u
Hct > 70% URGENT PHLEBOTOMY needed
-
-
-
-
Critical platelet parameters
Plts > 600k, further eval req.
Plts < 50k, increased risk of post-op bleeding
Plts > 2million RISK OF THROMBOSIS
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