drugs that primarily cause arterial and venous dilation through their action on peripheral sympathetic neurons
antihypertensive drugs
medications used to treat hypertension
cardiac output
amount of blood ejected from the left ventricle, measured in liters per minute
centrally acting adrenergic drugs
drugs that modify the function of the sympathetic nervous system in the brain by stimulating alpha2 receptors, which has a reverse sympathetic effect that causes decreased blood pressure
essential hypertension
elevated systemic arterial pressure for which no cause can be found and which is often the only significant clinical finding
also called primary or idiopathic hypertension
prodrug
a drug that is inactive in its administered form and must be metabolized to its active form in the body, generally by the liver to be effective
secondary hypertension
high blood pressure associated with a primary disease such as renal, pulmonary, endocrine, or vascular disease