Heparin

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  1. Heparin

    Name / Class
    Heparin

    Anticoagulant (unfractioned)
  2. Heparin

    Mechanism of Action
    Blocks the conversion of prothrombin to thrombin and the conversion of fibrinogen to fibrin.
  3. Heparin

    Onset of Action
    Peak Effect
    Duration
    Half-Life
    • Immediate
    • 2 - 3 minutes
    • 2 - 6 hours
    • 90 minutes
  4. Heparin

    Indications
    • Acute coronary syndrome
    • Pulmonary embolism
  5. Heparin

    Contraindications
    Known hypersensitivity to the drug and to beef/pork products
  6. Heparin

    Precautions
    • Active major bleeding
    • Thrombocytopenia
    • Use caution in:
    • Elderly Pts
    • Pts with increased risk of bleeding
    • Chronic alcoholism
    • Pregnancy
  7. Heparin

    Side Effects
    • Confusion
    • Edema
    • Dizziness
    • Bleeding complications
    • CP
    • Irregular heart beat
  8. Heparin

    Adult Dose
    • Acute STEMI & unstable angina:
    • 60 units/kg IV (max 4000 units), followed by 12 units/kg/hr (max 1000 units/hr).
    • NSTEMI & unstable angina:
    • 60 - 70 units/kg IV (max 5000 units), followed by 12 - 15 units/kg/hr infusion.
  9. Heparin

    Pedi Dose
    50 units/kg, followed by IV infusion based on lab values & body mass.
  10. Heparin

    Max Dose
    5000 units
  11. Heparin

    Routes / How Supplied
    IV, infusion

    unknown
Author
ID
207637
Card Set
Heparin
Description
Heparin drug study
Updated
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