Procainamide

Procainamide

Names / Class

Pronestyl

1A Sodium channel blocker, antiarrythmic
Procainamide

Mechanism of Action
- Slows conduction through myocardium.
- Elevates ventricular fibrillation threshhold.
- Suppresses ventricular ectopic activity.
Procainamide

Onset of Action
Peak Effect
Duration
Half-Life
- 10 - 30 minutes
- 15 - 20 minutes
- 3 - 6 hours
- 3 hours
Procainamide

Indications
- V-Tach with a pulse
- Pre-excited A-Fib
Procainamide

Contraindications
- 2nd & 3rd degree heart block
- Severe conduction system disturbances
- CHF
- Should be avoided in Pts with prolonged QT syndrome
Procainamide

Precautions
- Monitor CNS toxicity
- Hypotension (with IV infusion)
- Monitor BP
- Hypotensive effects may increase if given with antiypertensive meds
- Chance of neurotoxicity if given with Lidocaine
Procainamide

Side Effects
- Drowsiness
- Seizures
- Confusion
- Hypotension
- Anxiety
- Nausea
- Vomiting
- Convulsions
- Widening of QRS complex
- Bradycardia
- Heart block
- Respiratory & cardiac arrest
Procainamide

Adult Dose
20 - 50 mg/min until arrythmia suppressed.
- * D/C if:
- Arrythmia suppressed
- Hypotension
- QRS complex widened by 50%
- Total of 17 mg/kg given
- Slow IV bolus: 20 mg/kg followed by maintenance infusion.
- Maintenance Infusion: 1 - 4 mg/min
Procainamide

Pedi Dose

Not indicated
Procainamide

Max Dose

17 mg/kg
Procainamide

Route / How supplied
- Slow IV bolus
- IV drip
Vial

Author

Ritameeker

ID

206915

Card Set

Procainamide

Description

Procainamide / Pronestyl

Updated

2013-03-13T01:37:07Z

Show Answers