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Dopamine

  1. Dopamine

    Names / Class
    Intropin

    Sympathetic Agonist
  2. Dopamine

    Mechanism of Action
    • Increased cardiac contractility & HR (beta1)
    • Vasoconstriction (alpha)
    • = increased systolic BP & pulse pressure
  3. Dopamine

    Onset of Action
    Peak Effect
    Duration
    Half-Life
    • <5 minutes
    • 5 - 8 minutes
    • <10 minutes
    • 2 minutes
  4. Dopamine

    Indications
    • Hemodynamically significant hypotension: systolic 70 - 100 mmHg NOT resulting from hypovolemia, & cardiogenic shock.
    • Symptomatic bradycardia refractory to Atropine.
  5. Dopamine

    Contraindications
    • Hypovolemic shock in which fluid resuscitation has not occurred.
    • Pheochromocytoma (tumor in the adrenal gland).
  6. Dopamine

    Precautions
    • Severe tachyarrythmias
    • V-Fib
    • Ventricular irritability
    • Reduce dose if Pt taking MAOIs (type of antidepressant)
    • Beneficial effects lost when dose exceeds 20 mcg/kg/min
    • Can be deactivated with alkaline solutions such as sodium bicarbonate.
  7. Dopamine

    Side Effects
    • Arrythmias
    • HTN
    • Palpitations
    • Nervousness
    • Anxiety
    • HA
    • CP
    • Dyspnea
    • Nausea / Vomiting
    • ** Many side effects are dose related **
  8. Dopamine

    Adult Dose
    • Dilute:
    • 800mg in 500mL D5W
    • OR
    • 400mg in 250mL D5W (1600 mcg/mL)
    • 2 - 10 mcg/kg/min increased until BP improves or until max dose of 20 mcg/kg/min
    • IV drip should be piggybacked into an already established IV infusion
  9. Dopamine

    Pedi Dose
    2 - 20 mcg/kg/min
  10. Dopamine

    Max Dose
    20 mcg/kg/min
  11. Dopamine

    Route / How Supplied
    IV drip only - piggybacked into existing IV infusion

    Vial
Author
Ritameeker
ID
206896
Card Set
Dopamine
Description
Dopamine / Intropin
Updated

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