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Dopamine
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Dopamine
Names / Class
Intropin
Sympathetic Agonist
Dopamine
Mechanism of Action
Increased cardiac contractility & HR (beta1)
Vasoconstriction (alpha)
= increased systolic BP & pulse pressure
Dopamine
Onset of Action
Peak Effect
Duration
Half-Life
<5 minutes
5 - 8 minutes
<10 minutes
2 minutes
Dopamine
Indications
Hemodynamically significant hypotension
: systolic 70 - 100 mmHg NOT resulting from hypovolemia, & cardiogenic shock.
Symptomatic bradycardia refractory to Atropine.
Dopamine
Contraindications
Hypovolemic shock in which fluid resuscitation has not occurred.
Pheochromocytoma (tumor in the adrenal gland).
Dopamine
Precautions
Severe tachyarrythmias
V-Fib
Ventricular irritability
Reduce dose if Pt taking MAOIs (type of antidepressant)
Beneficial effects lost when dose exceeds 20 mcg/kg/min
Can be deactivated with alkaline solutions such as sodium bicarbonate.
Dopamine
Side Effects
Arrythmias
HTN
Palpitations
Nervousness
Anxiety
HA
CP
Dyspnea
Nausea / Vomiting
** Many side effects are dose related **
Dopamine
Adult Dose
Dilute
:
800mg in 500mL D5W
OR
400mg in 250mL D5W (1600 mcg/mL)
2 - 10 mcg/kg/min increased until BP improves or until max dose of 20 mcg/kg/min
IV drip should be piggybacked into an already established IV infusion
Dopamine
Pedi Dose
2 - 20 mcg/kg/min
Dopamine
Max Dose
20 mcg/kg/min
Dopamine
Route / How Supplied
IV drip only - piggybacked into existing IV infusion
Vial
Author
Ritameeker
ID
206896
Card Set
Dopamine
Description
Dopamine / Intropin
Updated
2013-03-13T00:29:16Z
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