What test is used to estimate the volume of fetal hemorrhage into maternal circulation?
How is test outcome determined?
Typically an acid elution (the separation of materials by washing) technique-Kleihauer-Betke test.
Hb F is resistant to acid elution (the separation of materials by washing,) adult Hb is not (On blood smear, fetal RBCs will appear bright pink while maternal RBCs will be almost translucent-maternal ghost cells.