Transmits sensory information to the CNS and produces facial and skeletal movements.
What does the autonomic nervous system do?
consists of sympatheric (fight and flight) and parasympatheric (rest and digest) --> handles arousing vs. calming functions
What are the four layers of protection for the brain?
1. Bone: (Brain protected by the skull, the spinal cord is encased in a series of interlocking bony vertabrae)
2. Meniges: (Dura mater (outer), Arachnoid membrane (middle), pia mater (inner)
3. Cerebrospinal Fluid (CSF): cushions the brain and spinal cord, continually being made and drained intothe circulatory system
4. Blood Brain Barrier: (comprised of cells of capillaries tightly joined with one another, prevents blood-borne subtances circulating in the body from crossing into the CNS)
What are the 5 components of a neuron?
1. Dendrites
2. Soma
3. Axon Hillock
4. Axon
5. Axon Terminal
What are dendrites and what do they do?
SpineBranching filaments of a neuron, they receive information from other cells
What is the soma?
The cell body, central part of the cell containing the nucleus
What is an Axon
single neruonal process that transmits information away from the cell
Axon Hillock is...
the site of origin of a nerve impulse
What is the ARP (Absoulte Refractory Period)
The voltage gated sodium channels are open/inactive and depolorization/repolorization -- nothing you do can trigger another action potential
What is the RRP?
During the RRP the voltage channels are returning to the closed state, but only a few channels will be closed so it requires a very strong stimulus to trigger a new action potential.
What is a synaptic cleft?
Small space between the axon terminal andthe post synaptic membrane of the receptor cell
What is a presynaptic membrane
membrane of the axon terminal, encloses the synaptc vesicles that contain neurotransmitters
Postsynaptic membrane
Contrains receptor molecules that recieve chemical messages from the presynaptic cell
What is EPSP
Excitatory postsynaptic potential: causes a depoloarization (+ions flow into neruron) of the postsynaptic target
Inhibitory postsynaptic potential (IPSP)
Causes a hyperpolarization (+ions flow out of neuron) of the postsynaptic target
Neurotransmitters decativation occurs in 3 ways
1. Reuptake (reabsorption of a neurotransmitter by a transporter of a presynaptic neruron)
2. Enzymatic degradation
3. Diffusion
What is a synapse?
Connection between neurons and other cells
What is a synaptic cleft?
Space between neurons, most neurons don't connect physically.
Axon terminal is...
the end of an axon, forms the presynaptic protion of the synapse. Is close to the dendritic spine of a neighboring neuron.
What are the 5 types of glial cells?
1. Ependymal cell: (Samll, ovoid; secretes CSF)
2. Astrocyte: (Star shaped, symmetrical; nutritive and support function)
4. Oligodendrogilial cell: (Asymmetrical; forms insulating myeling around axons in brain and spinal cord)
5. Schwann cell: (Asymmetrical; wraps around peripheral nervs to form insulating myelin)
Cytoarchitecture differs across regions and layers of the cortex. T/F?
T
Why do we divide the brain intoanatomical regions (Brodmann areas)
Because of reginonal differencs in the cytoarchitecture of neurons
Gray matter is comprised of ...
cell bodies and capillaries
Afferent neurons carry information ...
toward (recieve)
Efferent neurons carry info ...
Away (send)
White matter is...
axons covered with glial cells
A tract is...
a large collection of axons, aka. a fiber pathway (distinctively white)
Nucleus/nuclei are ...
many neruons grouped together (distinctively gray)
Dorsal Root of the spinal cord has what types of fibers? These fibers carry sensory information where?
Afferent (receiving), sensory to the brain
Ventral Root of the spinal cord has what types of fibers? These fibers carry sensory information where?
Efferent (sending), motor information to the body
The SNS recieves what type of information? Is largely voluntary or involuntary?
Sensory & Voluntary
The Brain Stem consists of what three areas?
1. Hindbrain
2. Midbrain
3. Diecephalon
The forebrain consists of what three parts
1. Basal Ganglia
2. Cerebral Cortex
3. Limbic Lobe
The brainstem begins where?
begins where the spinal cord enterst the skull
The Hindbrain consists of what four parts?
1. Cerebellum
2. Reticular Formation
3. Pons
4. Medulla
The cerebullum is associated with?
Learning and coordinateing/ sequencing skilled movements; posture and balance
The pons is responsible for?
sleep-wake regulation; locomotion
The reticular formation does what?
Maintains general arousal/consciousness
The Medulla does what?
maintains vital body funtctions (respirations, heart rate etc.)
The midbrain consists of two main stuctures?
1. Tectum (roof) (located dorsally)
2. Tegmentum (floor) (located ventrally)
The tectum consists of what two structures and what are they responsible for?
1. Superior colliculi: processes visual input
2. Inferior colliculi: processes auditory input
Colliculi mediate responese to what type of input and what is their function?
Sensory inputs, and they orient us to visual and auditory signals.
The tegmentum (floor) is comprised of what three parts and what is their purpose?
1. Red nucleus: controls limb movement
2. Sustantia nigra: dopaminergic neurons, involved in reward, control of movement
3. Periaaqueductal gray matter: controls species specific behavior (eg. sexual behavior) modulates pain response.
The diencephalon consists of what three structures and what are their functions?
1. Hypothalamus: (Involvely in nearly all aspects of motivated behavior (eg. hunger,thirst, sexual behavior)
2. Epithalamus: (Poorly understood - involved in bio-rhythms, huger,thirst)
3. Thalamus: (Relays incoming (afferent) senesory information to appropiate targets; relays infomraiton between cortical areas; relays information between forebrain and brainstem.
Major Portions of the Brain include ...
1. Cerebrum
2. Cerebellum
3. Brainstem
The forebrain consists of what 3 main structures and what are their functions?
1. Basal Ganglia (Involuntary motor control, habitual learning action selection (selecting the correct action at the correct time)
Neocortical regions are connected by four types of axon projections, what are they?
1. Long ipsilateral connections between one lobe and another (fasciculi)
2. Relatively short connections between one part of a lobe and another
3. Inter-hemispheric (bridging) connections between homotopic points in contralateral hemispheres
4. Connections between cortical areas through the thalamus
Ipsilateral means?
Same Side
Contralateral means?
Opposite sides
Axon fibers make what 3 types of connections?
1. Connections between one lobe of the brain to another
2. one part of a lobe to another part
3. one hemishpere of the brain to another
What is an action potential?
The signal that goes through the axons going from place to another place.
Are cations negative or positive?
positive (Na+. K+)
Are anionos negative or positive
negative, (CL-)
What is depolorization?
When membrane channel opens and positive sodium ions rush into the cell and change the membrane potential and make them positive. This is the first phase of the action potential.
What happens in the second phase of the action potential? (Repolarization)
After Na+ comes in the charge is very very positive, because the membrane potential is that positive, the voltage gated potassium channels open and K+ escapes because it wants the charge to be negative. This is repolarization.
What is the first stage of the action potential?
Depolarization
What is the second phase of the action potential?
Repolarization
What is the last phase of the action potential?
Hyperpolarization
What is hyperpolarization?
As K+ escapes we overshoot and go lower than the resting membrane potential. Becomes OVERpolarized.
Sodium Potassium Pump does what?
Pumps 3 Na+ ions out and 2 K+ ions in and bring the potential back to its resting state.
Synaptic Vesicles contain what?
Neurotransmitters
What is the pre-synaptic membrane?
Membrane that comes right before the space (synaptic cleft)
Membrane that comes after the synaptic cleft?
post-synaptic membrane
Reuptake:
reabsorption of a neurotransmitter by a transport of a presynaptic neuron. Allows recyling of neurotransmitters
What are the 7 major neurotransmitters?
1. Acetylcholine (ACh): PNS; activates muscules // CNS; forms the cholinergic sytem, role in the enchancement of sensory perceptions sustaining memory and attn.