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Immunology Intro
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What are the primary functions of the immune system, and consequently how can it go wrong?
Protect the body from foreign invasion- has the ability to identify self from non-self
Clean up debris- isolate and phagocytosis
Prepare tissue for healing-inflammation, tissue restoration or scarring
Which antibodies are responsible for recognizing foreign invaders
T lymphocytes and B lymphocytes can recognize any foreign antigen to fight infection
What do kinins/bardykinins do?
Cause inflammation
Wall off pathogens
Organs of immunity: thymus
T Lymphocytes migrate to the thymus to mature and then are released into circulation
Organs of immunity: spleen
Lymph filtration
Recycles iron from RBCs
White cells for blood borne protection
Blood reservoir
What do you need to know about leukocytes
Granulocytes (55-60%)
Named after granules in the cytoplasm and perform phagocytosis
Immature Neutrophils are called “Bands”, requiring 14 days for maturity
What do you need to know about granulocytes?
Lymphocytes- Granulocytes with “Natural Killer”
abilities- small Lymphocytes are T and B Cells
What type of granulocyte is involved in allergic rxn and parasite invasion?
eosinophils
What is a basophil?
stimulate inflammatory response- have histamine, bradykinin and heparin granules
Mast cells are basophils found in the tissues
What's a neutorphil?
Granulocyte
Chief phagocytes of early inflammation
Shoot lysosmal granules dissolve cellular debris to prepare site for wound healing
What are agranulocytes?
Most powerful at phagocytosis
Do not contain granules, can ingest dead host cells such as blood cells
Monocytes and macrophages are agranulocytes
Monocyte is immature macrophage
--replenish macrophages
--respond quickly to inflammation
What do macrophages do?
Significantly initiate inflammatory response
Larger and more phagocytic than monocytes
Author
alyn217
ID
205123
Card Set
Immunology Intro
Description
Adult MedSurg 2
Updated
2013-03-05T17:04:03Z
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