pharma II test II BPD

3 catergories of BPD
- bipolar I
- manic and mixed episodes
- usually depressive episodes
- bipolar II
- hypomanic or depressive episodes
- not mainic or mixed episodes
- rapid-cycling bipolar episodes
- 4 or more episodes of any sort each year
- difficult to treat
biggest problem with treating BPD
- compliance
- short term hospitalization
- long-term prophylactic therapy
- education for patient and family
"mood stabilizers" for BPD
- lithium
- valproate
- lamotrigine
- atypicals
2 main MOA of lithium
- 1. inhibit 2^nd messengers; IP₃ & DAG
- 2. alter ion distrib, sub for NA
target plasma levels of lithium

0.6-1.4 mEq/L
6 antipsychotics approved for BPD
- ziprasidone
- aripiprazole
- quetiapine
- risperdone
- olanzapine
- olanzapine/fluoxetine

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pharma II test II BPD

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pharma II test II BPD

Updated

2013-03-07T06:03:54Z

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