Potent rx NSAID that should not be used for more than 5 days:
Toradol
Common OTC NSAID with a 6-8 hour half life:
naproxen
Major advantage of Tylenol over the NSAIDs:
no stomach ulcers
Drug rx for RA as well as cancer:
methotrexate
Injectable drug that inhibits tumor necrosis factor:
Humira
Life-threatening adverse effect of opiate overdose
respiratory depression
More potent opiate than morphine w/ lower incidence of nausea:
hydromorphone
About 7% of the american population do not get very good pain relief from codeine because:
they lack metabolizing enzyme CYP 2D6
______ is a morphine derivative that was the most commonly rx drug in the country in 2005 and is the drug of choice of Dr. House. It is almost always combined with ______.
hydrocodone
acetaminophen
Another common morphine derivative available in long-acting form that has become a popular street drug and was publicized by Rush Limbaugh and was reformulated in fall 2011 because:
oxycontin
people could crush them for faster high
Opiate that is currently drug of choice for the pain associated with childbirth:
Fentanyl
Antitussive with mild hallucinogenic properties:
Robitussin
______ was originally developed as an alternative to heroin that did not require needles but has been increasingly used as a pain med in its own right. It has (rapid/slow) onset.
methadone
slow
Opiate that is commonly rx for cancer patients and those with frequent vomiting:
Fentanyl
Antidote for opium overdose:
Narcan
Opioid that is used to tx diarrhea:
Imodium
There's little likelihood Imodium can be abused because:
it isn't absorbed outside the GI tract
Common local anesthetic in the dental office:
lidocaine
Cocaine causes major damage to the noses of regular snorters due to its ________ properties.
vasocontrictive
Tagamet, Pepcid, and Axid are examples of ______ family of drugs which are used to reduce ulcer pain.
histamine-2 antagonists
Family name of drug family other than histamine 2 antagonists that reduce ulcer pain:
proton pump inhibitors
Generic proton pump inhibitors all end in:
-prazole
Commonly prescribed proton pump inhibitor:
Prilosec or Nexium
Prior to the 1970's most medical research was funded by the ________.
federal gov't
What alternatives to an implanted defibrillator are suggested by Dr. Abramson:
diet and excercise
How did drug makers make sure Nexium appeared more efficacious than Prilosec:
they gave twice the dosage of Nexium
In what way is the list of authors on a medical article misleading?
medical articles can by written by ghostwriters who were not involved in the research
which proton pump inhibitor is the biological right hand of Prilosec?
Nexium
The vast majority of ulcers are due to infection with:
Helicobacter pylori
tx with antibiotics
First H2 antagonist that has largely been replaced:
Tagamet
Common adverse effect of Tagamet:
inhibition of CYP 450
Synthetic opioid that causes less constipation that morphine:
Demerol
Synthetic opioid that was popular for dental pain but has since bene pulled off the market:
Darvon
The 2 classes of local antithetics based on organic functional groups:
Esters (benzocaine, cocaine, Novacaine)
Amides (lidocaine)
Ester that is strictly a topical anesthetic:
benzociane
Family of drug for tx of migraines:
tryptan family
How to local anesthetics work:
block sodium channel proteins form inside the cell