Med Chem III quiz 4

Extensive first pass when given orally unless resistant to conjegation

Resistant to conjegation ie codeine
Fentanyl

Most lipophillic agant transdermal absorption is very good also very dangerous
Labor and dlivery-BBB is poorl developed in infants can lead to

significant respiratory depression
Metabolism of Anlagesics

glucronides, N- and Odemethylation occurs in the liver followed by renal excretion
CYP2D6 polymorphisms

issue and durg clearance rate and side effect profiles
Three sypmptom of a narcotic over dosage
- CNS-respiratory Depression
- CNS- Miosis- pinpoint pupils
- PNS- Decreased bowl sounds due to relaxed smooth muscle

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ljohnstad

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Med Chem III quiz 4

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Med Chem III quiz 4 ANALGESICS

Updated

2013-02-25T03:50:13Z

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