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a. in closed system, exchange occurs at __
capillaries
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i. Capillary is a __ that we’re talking about
ii. __ is great
- capillary bed
- Surface area
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i. The greater the __ of an organ, the more capillary beds
1. There are more places for exchange because, if the tissue is __, it has a great demand for __and a desire to __
- metabolic rate
- metabolically active
- oxygen and nutrients
- get rid of wastes
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Two pressures operate in blood
hydrostatic and osmotic
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Hydrostatic Pressure
- 1. Blood pressure; fluid pressure
- a. Pressure exerted by the fluid on the walls of the vessel
- i. How fast or slow your heart is flowing
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Where does hydrostatic change pressure?
1. Decreases across the capillary (BPBà capillaries
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Hydrostatic always exerts force where?
out of container it's in
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1. More material leaving capillary at __ due to __
a. What can’t get out are __; they’re too big
2. Forces blood out
- arterial end
- greater pressure
- proteins
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i. Osmotic pressure of interstitium, under normal conditions, is __
1. If there were one there, it would __
- zero
- exert force into where solutes are
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Explain osmotic
- 1. Due to the ionic concentration of the solution (solute concentration and ionic, not just ionic)
- 2. Force is going to cause water to move inward
- a. There are more solutes inside
- i. Solute concentration determines flow
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1. Osmotic pressure opposes __; __the direction where the solutes are
2. Does not change across the __; STAYS THE SAME __
- hydrostatic pressure
- in
- capillaries
- BECAUSE PROTEINS DO NOT LEAVE
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Explain pressure on the arterial side.
- 1. AS LONG as HPb is greater than OPB, you’ll have material leaving the capillaries
- a. If the HPb is larger than than OPB, the net effect will be coming out
- b. The materials get dumped off
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Venous Side
- 1. The HPB is now lower than OPB, the net effect will be into the capillary
- a. CO2 and waste products to come back in
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Venous Side and water
- i. Not all water that leaves at arterial end returns to the blood at the venous end of capillary
- 1. The lymphatic capillaries in the area will pick up the excess water and eventually dump it back into cardiovascular system
- b. This becomes important in pathological condition
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