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Nitrates/Nitrites Mechanism of Action
- Dilate all blood vessels
- ~coronary arteries
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Nitrates/Nitrites Indications
- stable, unstable, and vasospastic angina
- can prevent
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Nitrates/Nitrite Contraindications
severe anemia, closed-angle glaucoma, hypotension, severe head injury
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Nitrates/Nitrite Adverse Effect
- headache, hypotension
- reflex tachycardia
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Beta-Blocker mechanism reaction
block beta 1 receptos on the heart
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Beta-blocker Indications
- exertional angina,
- antihypertensive, cardiac dysrhythmias, cardioprotective effects
- migraine headaches, essential tremors, stage fright
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Beta-blocker contraindications
- systolic heart failure and serious conduction disturbances
- bronchial asthma, diabetes mellitus, reduced mental alertness, peripheral vascular disease
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Beta-Blocker Adverse Effects
- decrease in heart rate, cardiac output, cardiac contractility, bronchoconstriction
- increased airway resistance
- cardiovascular- hypotension, second or third degree heart block, heart failure
- Metabolic- altered glucose and lipid metabolim
- CNS- dizziness, fatigue, mental depression, lethargy, drowsiness, unusual dreams
- Other: impotence, wheezing, dyspnea
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Calcium channel Mechanism of Action
cause coronary artery and peripheral arterial vasodilation
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Calcium channel Indications
- short term atrial fibrillation and flutter, migraines, Raynaud's disease
- angina, hypertension, supraventricular tachycardia
- coronary artery spasms
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Calcium channel Contraindications
acute MI, AV block, hypotension
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Calcium Channel Adverse Effects
hypotension, palpitations, tachycardia, bradycardia, constipation, nausea, dyspnea
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Calcium Channel Interactions
grapefruit juice
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