1. Home
  2. Flashcards
  3. Preview

Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) in DSM III

  1. At what cell count is an immunodeficiency considered AIDs?
    < 200 cells/mm3
  2. What is an indicator of normal immune status?
    > 500 cells/mm3
  3. When is resistance testing recommended?
    • 1)  initial therapy
    • 2)  pregnant women
    • 3)  therapy failure
  4. When is resistance testing not recommended?
    • 1) If the viral load is less than 1,000 copies
    • 2)  If the patient has been off treatment for more than 4 weeks
  5. What are some benefits of ART?
    • 1)  restore/maintain the immune system
    • 2)  lower the risk of transmission
    • 3)  decreases the progression of hepatitis
    • 4)  reduces chance of non-Hodgkins lymphoma
    • 5)  decreases the chance of developing cardiovascular disease
  6. What are some potential limitations of early therapy?
    • 1)  cost
    • 2)  long duration of therapy (lifetime)
    • 3)  side effects
  7. Ziagen
    Abacavir
  8. Videx
    Didanosine
  9. Emtriva
    Emtricitabine
  10. Epivir
    Lamivudine
  11. Zerit
    Stavudine
  12. Viread
    Tenofovir
  13. Retrovir
    Zidovudine
  14. Sustiva
    Efavirenz
  15. Viramine
    Nevirapine
  16. Intelence
    Etravirine
  17. Edurant
    Rilpivirine
  18. Reyataz
    Atazanavir
  19. Prezista
    Darunavir
  20. Lexiva
    Fosamprenavir
  21. Norvir
    Ritonavir
  22. Kaletra
    Lopinavir/r
  23. Viracept
    Nelfinavir
  24. Invirase
    Saquinavir
  25. Aptivus
    Tipranavir
  26. Fuzeon
    Enfuvirtide
  27. Selzentry
    Maraviroc
  28. Isentress
    Raltegravir
  29. Stribild
    Elvitegravir/Cobicistat/Emtricitabine/Tenofovir
  30. What drugs work by being a an analog of a DNA nucleoside and competes with the nucleosides incorporated into DNA in order to inhibit the reverse transcriptase (NRTIs)?
    • 1)  Ziagen (Abacavir)
    • 2)  Videx (Didanosine)
    • 3)  Emtriva (Emtricitabine)
    • 4)  Epivir (Lamivudine)
    • 5)  Zerit (Stavudine)
    • 6)  Viread (Tenofovir)
    • 7)  Retrovir (Zidovudine)
  31. Which drugs must be taken with food?
    • 1)  Intelence (etravirine)
    • 2)  Norvir (Ritonavir)
    • 3)  Reyataz (Atazanavir)
    • 4)  Prezista (Darunavir)
    • 5)  Viracept (Nelfinavir)
    • 6)  Aptivus (tipranavir)
    • 7)  Stribilid (elvitegravir)
  32. Which drug must be taken half an hour before of 2 hours after meals?
    Videx (didanosine)
  33. What drug must be taken on an empty stomach?
    Sustiva (efavirenz)
  34. Which drug must be taken within 2 hours of a meal?
    Invirase (saquinavir)
  35. Which drugs causes hepatitis if discontinued?
    • 1)  Emtriva (emtricitabine
    • 2)  Epivir (lamivudine)
    • 3)  Viread (tenofovir)
  36. Which drugs shouldn't be given in patients with sulfa allergies?
    • 1)  Lexiva (fosamprenavir)
    • 2)  Aptivus (tipranavir)
    • 3)  Prezista (darunavir)
  37. Which nucleoside reverse transcriptase inhibitor (NRTI) does not require a renal adjustment?
    Ziagen (abacavir)
  38. Which drugs should you avoid alcohol when taking?
    • 1)  Ziagen (abacavir)
    • 2)  Videx (didanosoine)
    • 3)  Sustiva (efavirenz)
  39. Which drugs are 3A4 substrates?
    • 1)  Edurant (rilpivirine)
    • 2)  Selzentry (maraviroc)
  40. Which drugs are 3A4 inhibitors?
    Norvir (ritonavir)
  41. Which drugs are 3A4 inducers?
    • 1)  Intelence (etravirine)
    • 2)  Viramune (nevirapine)
  42. Which drugs are 3A4 substrates, inducers, and inhibitors?
    • 1)  Sustiva (efavirenz)
    • 2)  Lexiva (fosamprenavir)
  43. Which drugs are 3A4 substrates and inducers?
    Aptivus (tipranavir)
  44. Which drugs are 3A4 substrates and inhibitors?
    • 1)  Reyataz (atazanavir)
    • 2)  Prezista (darunavir)
    • 3)  Crixivan (indinavir)
    • 4)  Viracept (nelfinavir)
    • 5)  Kaletra (lopinavir/r)
    • 6)  Invirase (saquinavir)
  45. What are some side effects associated with Videx (didanosine)?
    • 1)  pancreatitis
    • 2)  peripheral neuropathy
  46. What are some side effects associated with Emtriva (emtricitabine)?
    hyperpigmentation
  47. What are some side effects associated with Zerit (stavudine)?
    • 1)  peripheral neuropathy
    • 2)  lipoatrophy
    • 3)  pancreatitis
  48. What are some side effects associated with Viread (tenofovir)?
    • 1)  renal insufficiency
    • 2)  osteomalacia
  49. What are some side effects associated with retrovir (zidovudine)?
    bone marrow suppression
  50. Which drugs work by inhibiting reverse transcriptase noncompetitively (NNRTIs)?
    • 1)  Sustiva (efavirenz)
    • 2)  Intelence (etravirine)
    • 3)  Viramune (nevirapine)
    • 4) Edurant (relpivirine)
  51. What are some side effects associated with Sustiva (efavirenz)?
    • 1)  rash
    • 2)  CNS effects
    • 3)  Contraindicated in the first trimester
  52. What are some side effects associates with Intelence (etravirine)?
    rash
  53. What are some side effects associated with Viramune (nevirapine)?
    • 1)  rash
    • 2)  hepatotoxicity
  54. What are some side effects associated with Edurant (relpivirine)?
    rash
  55. Which drugs inhibit the protease enzymes found in HIV viruses (PIs)?
    • 1)  Norvir (ritonavir)
    • 2)  Reyataz (atazanavir)
    • 3)  Prezista (darunavir)
    • 4)  Lexiva (fosamprenavir)
    • 5)  Crixivan (indinavir)
    • 6)  Viracept (nelfinavir)
    • 7)  Kaletra (lopinavir/r)
    • 8)  Invirase (saquinavir)
    • 9)  Aptivus (tipranavir)
  56. What are some side effects associated with Norvir (ritonavir)?
    GI intolerance
  57. What are some side effects associated with Reyataz (atazanavir)?
    • 1)  Indirect hyperbilirubinemia
    • 2)  Skin rash
    • 3)  Most lipid friendly
  58. What are some side effects associated with Prezista (darunavir)?
    Skin rash
  59. What are some side effects associated with Crixivan (indinavir)?
    • 1)  Kidney stones
    • 2)  Hyperbilirubinemia
  60. What are some side effects associated with Viracept (nelfinavir)?
    Diarrhea (severe)
  61. What are some side effects associated with Kaletra (lopinavir/r)?
    • 1)  GI upset
    • 2)  QT prolongation
  62. What are some side effects associated with Invirase (saquinavir)?
    GI intolerance
  63. What drug inhibits entry of HIV-1 into cells by inhibiting fusion of viral and cellular membranes?
    enfuvirtide (Fuzeon)
  64. What drug prevents HIV infection by blocking CCR5 receptors?
    maraviroc (Selzentry)
  65. What are the side effects associated with Selzentry (maraviroc)?
    • 1)  hepatotoxicity
    • 2)  orthostatic hypotension
    • 3)  rash
  66. What drugs works by preventing viral replication by inhibition viral DNA insertion into the host's cellular genome by blocking integrase insertion?
    • 1)  Isentress (raltegravir)
    • 2)  Stribild (elvitegravir)
  67. What side effects are associated with Isentress (raltegravir)?
    • 1)  CPK elevation
    • 2)  muscle weakness
    • 3)  ache
    • 4)  rhabdomyolysis
  68. What side effects are associated with Stribild (elvitegravir)?
    • 1)  nausea
    • 2)  diarrhea
  69. Combivir
    • 1)  zidovudine
    • 2)  lamivudine
  70. Trizivir
    • 1)  zidovudine
    • 2)  epivir lamivudine
    • 3)  abacavir
  71. Epzicom
    • 1)  lamivdine
    • 2)  abacavir
  72. Truvada
    • 1)  tenofovir
    • 2)  emtricitabine
  73. Atripla
    • 1)  tenofovir
    • 2)  emtricitabine
    • 3)  efavirenz
  74. Complera
    • 1)  tenofovir
    • 2)  emtricitabine
    • 3)  relpivirine
  75. Stribild
    elvitegravir
  76. Which drugs should not be used if the CrCl is less than 50 mL/min?
    • 1)  Combivir
    • 2)  Trizivir
    • 3)  Epzicom
    • 4)  Atripla
    • 5)  Complera
    • 6)  Stribild
  77. Which drugs should not be used if the CrCl is less than 30 mL/min?
    1)  Truvada
Author
mcucullu
ID
201810
Card Set
Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) in DSM III
Description
All material pertaining to HIV and AIDS in the DSM III course offered at XUCOP.
Updated

  1. Home
  2. Flashcards
  3. Preview