MED-Diltiazem

Functional Class

Class IV antidysrhythmic (Calcium channel blocker)
Mechanism of Action
- Inhibits calcium ion influx through slow channels into the myocardial cells and arterial smooth muscle
- Causes intracellular calcium to remain at sub-threshhold levels
- Reduces peripheral vascular resistance by inhibiting the arterial smooth muscle
- Inhibits coronary artery spasm
- Slows SA and AV node conduction without effecting atrial action potential
Indications
- SVT refractory to adenosine
- Rapid A-Fib/A-Flutter
Contraindications
- Hypersensitivity
- Sick sinus syndrome
- 2nd and 3rd degree AV block
- Hypotension
- WPW
- Wide complex tachycardia
Precautions
- Avoid in patients on oral beta blockers
- Monitor for hypotension resulting from peripheral vasodilation
- Use with caution in CHF patients
Side Effects
- Chest pain
- Bradycardia
- Hypotension
- Syncope
- CHF
- Dysrhythmias
- N/V
- Headache
- Sweating
- Dizzness
- Dyspnea
- 2nd and 3rd degree AV block
- Palpitations
Interactions

Beta blockers
Dose and Route
- Bolus:
- 0.25 mg/kg slow IVP, may repeat in 15 mins at 0.35 mg/kg slow IVP
- Infusion:
- 5-15 mg/hr, titrate to heart rate

Author

amerelman

20166

Card Set

MED-Diltiazem

Description

MED-Diltiazem

Updated

2010-05-21T15:19:13Z

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