-
-
Empiric
1mo-60yo
- ceftriaxone or cefotaxime +
- vanc
-
Empiric
> 60yo
- ceftriaxone or cefotaxime +
- vanc +
- Amp
-
Empiric
Neurosurgery
- Vanc +
- ceftazidime, cefepime or meropenem
-
Empiric
Open head trauma
- cetriaxone or cefotaxime +
- vanc
-
Empiric
Immunocompromised
- Vanc +
- Amp +
- cefepime or meropenem
-
PSSP
MIC < 0.06
- Pen G
- amp
- ceftriaxone, cefotaxime
- chloramphenicol
-
PISP
MIC 0.12-0.1
- ceftriaxone, cefotaxime
- cefepime
- meropenem
- linezolid
- moxifloxacin
-
PRSP
MIC >2
- Vanc + ceftriaxone
- vanc + cefotaxime
- ceftriaxone or cefotaxime + moxie
- meropenem
- linezolid
-
Group B strep
- Amp +/- gent
- PCN +/- gent
- ceftriaxone, cefotaxime
- chloramphenicol
-
MSSA
- Nafcillin
- oxacillin
- vanc
- meropenem
- linezolid
-
-
Listeria
- Amp +/- gent
- PCN +/- gent
- bactrim
- vanc + gent
-
Neisseria Meningitidis
pen susceptible
- Pen G
- Ampicillin
- ceftriaxone, cefotaxime
- chloramphenicol
-
Neisseria meningiditis
pen resistant
- Ceftriaxone
- cefotaxime
- chloramphenicol
- meropenem
- FQ
-
H. flu
b-lactamase negative
- amp
- ceftriaxone, cefotaxime
- chloramphenicol
-
H. Flu
B-lactamase positive
- ceftriaxone, cefotaxime
- cefepime
- FQ
- chloramphenicol
-
Enterobacteriaceae
- ceftriaxone (can select for stably depressed)
- cefotaxime
- cefepime
- FQ
- meropenem
- aztreonam
-
p. aeruginosa
- cefepime + tobra
- Ceftazidime + tobra
- mero + tobra
- pip/tazo tobra
- colistin
-
prophylaxis
neisseria meningitidis
-
-
Cryptococcal
HIV -
- ampho B + flucytosine then fluconazole
- Ampho B + flucytosine
- ampho B
- liposomal ampho B
-
Cryptococcal
HIV +
- Ampho B +/- flucytosine then fluconazole
- fluconazole
- fluconazole + flucytosine
-
-
Varicella zoster
acyclovir
-
CMV
Ganciclovir + foscarnet
-
-
Brain Abcess d/t otitis media
- ceftriaxone or cefotaxime +
- metro
-
Brain Abcess d/t sinusitis
- ceftriaxone or cefotax +
- metro
-
Brain Abcess d/t dental infection
pcn +metro
-
Brain Abcess d/t penetrating trauma or postneurosurgical
vanc + ceftriaxone or ceftaxime
-
Brain Abcess d/t penetrating trauma or postneurosurgical
w/ risk of psudomonas
vanc + cefepime of ceftazidime
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