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What are estrogens used for?
used for contraception, relief of postmenopausal symptoms as hot flashes and prevention of postmenopausal osteoporosis.
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Premarin
Estrogen used for many reasons.
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How do oral contraceptives work?
Thickening the cervical mucous to slow sperm passage, alters the endometrial lining to prevent implantation and inhibits ovulation.
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What are some contraindication of estrogen therapy?
Estrogen dependent cancer, thrombeoembolic disease.
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medroxyprogesterone acetate (Provera)
Progesterone. induces favorable condistions for fetal growth and development and maintain pregnancy.
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norethindrone (Micronor)
Progesterone. induces favorable condistions for fetal growth and development and maintain pregnancy.
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Megestrol acetate (megace)
Progesterone. induces favorable condistions for fetal growth and development and maintain pregnancy.
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What is an adverse effect similar to estrogen of progesterones?
Thromboembolic events (MI, pulmonary embolism, thrombophlebities, CBA)
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Progesterones are preg category ?
X
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Besides thromboembolic events, what is another side effect of Hormonal contraceptives?
HTN
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Tetolactone (Teslac)
Androgen used for testosterone effects.
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Finasteride (Proscar)
5-alpha reductase inhibitor. Decreases usable testosterone and causes a reduction of the prostate size and increases hair growth.
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Dutasteride (avodart)
5-alpha reductase inhibitor. Decreases usable testosterone and causes a reduction of the prostate size and increases hair growth.
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What are a couple of side effects of 5- alpha reducatse inhibitors such as finasteride and dutasteride
Decreased libido/ ejac amt and gynecomastia.
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Tamsulosin (Flomax)
Alpha 1- adrenergic antagonists. For BPH. Drecreases mechanical obstruction of the urethra bey relaxing smooth muscles of the bladder neck and prostate.
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Silodosin (Rapaflo)
Alpha 1- adrenergic antagonists. For BPH Drecreases mechanical obstruction of the urethra by relaxing smooth muscles of the bladder neck and prostate.
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A pt taking a alpha 1- adrenergic antagonist should be monitored for what?
Hypotension
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Vardenfil (Levitra)
PDe5 inhibitor used for erectile dysfunciton.
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What are a couple side effects of PDEF inhibitors such as levitra, cialis and viagra>
MI, sudden death and priapism.
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What type of drug is Isosorbide Dinitrate (Isordil)?
Organic nitrate!!! dont take w/ viagra
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PDE5 inhibitors (viagra) are contraindicated in who?
People taking nitrates. Can lead to fatal hypotension.
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When should pt's take PDE5 inhibitors (viagra, levitra, etc..)
1 hour before sexual activity.
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