Resting and Action Potential;

major cation inside

major cation outside

excess of positive outside and negative inside the membrane; gives rise to an electrical potential difference which ranges from about 60-70 mV

type of channel that opens when the membrane potential changes beyond threshold value

opens when bound by specific agonist, initiates depolarisation or hyperpolarization of the plasma membrane

RMP of nerve cells

membrane becomes permeable to sodium ions overshoot beyond zero and becomes somewhat positive

sodium ion channels close, potassium open

membrane potential becomes more negative than the original resting potential 

travel away from the stimulus; all or nothing principle

fast channels that is responsible for the spike portion of action potential 

excessive flow of potassium; carries tremendous numbers of (+) charges to the outside creating more (-) inside 

jump of action potential; new stimulus can't be elicited because sodium channels are inactivated