-
Inotropes:
Positive:
Negative:
Inotropes alter contraction force.
Positive: Stronger Contraction
Negative: Weaker Contraction
-
Chronotropes:
Positive:
Negative:
Chronotropes alter rate
Positive: Increases Rate
Negative: Decreases Rate
-
Cardiac Glycosides
_____ Inotrope _____ Chronotrope
Use:
- Cardiac Glycosides
- Positive Inotrope
- Negative Chronotrope
- Increases contraction/decreases rateUse: treats heart failure
-
Cardiac Glycosides
Digitalis Drugs:
1.
2.
3.
Treats:
- Cardiac Glycosides
- Digitalis Drugs:
- 1. Digoxin
- 2. Cardoxin
- 3. Lanoxin
- Treats: Congestive Heart Failure, Atrial Fibrillation
-
Cardiac Glycosides
Catecholamines "____________________"
Use:
_______ Inotrope _______ Chronotrope
1.
TX:
2.
TX:
3.
TX:
4.
- Cardiac Glycosides
- Catecholamines "sympathamimetric"
- Use: Mimics sympathetic nervous system "Fight or Flight"
- Positive Inotrope Positive Chronotrope
- Increase contraction force increase rate
- 1. Epinephrine
- TX: CPA
- 2. Dopamine (Dopamine HCL, Inotropin)
- TX: Acute heart failure, shock, renal failure.
- -Natural
- 3. Dobutamine (Dobutrex)
- TX: Acute heart failure, shock, renal failure.
- -Synthetic
- 4. Isoproterenol (Isuprel)
- -Causes: muscle tremors, bronchoconstriction
- -Old drug, rarely used.
-
Antiarrhythmics
Local Anesthetics
1.
TX:
2.
TX:
Species:
3.
TX:
Species:
Antiarrhythmics
- Local Anesthetics
- 1. Quinidine (Cardioquin, Quindex)
- TX: Atrial Fibrillation
- 2. Procainimide (Pronestryl, Procainimide -SR)
- TX: VPC, Ventricular Tachycardia
- Species: Feline
- 3. Lidocaine (Lidocaine, Xylocaine)
- TX: VPC, Ventricular Tachycardia
- Species: Canine
-
Antiarrythmics
Beta-Adrenergic Blockers
TX:
1.
Antiarrythmics
Beta-Adrenergic Blockers - TX: Hypertrophic, cardiomyopathy, some arrythmias
- 1. Propranolol (Inderol, Intensol)
-
Antiarrhythmics
Action Potential Prolongation
________ Chronotrope
1.
2.
TX:
Antiarrhythmics
- Action Potential Prolongation
- Negative Chronotrope
- Decreases heart rate1. Bretylium (Bretylol) - chemical defribrillation
- 2. Amiodarone (Cardarone)
- TX: Ventricular Tachycardia, Ventricular Fibrillation
-
Vasodialators
Use:
Angiotensis:_______ inhibitor
TX:
1.
- Vasodialators
- Angiotensis: ACE Inhibitor
- TX: Congestive Heart Failure, Hypertension
- 1. Enalapril (Enacard)
- Decreases workload, decreases blood pressure
-
Vasodialators
Arteriole Dialators
1.
- Vasodialators
- Arteriole Dialators
- 1. Hydralazine (Apresoline)
-
Vasodialators
Venodialators
1.
Form:
Use:
Vasodialator
Venodialators - 1. Nitroglycerin(Nitro-bid, Nitrol)
- Use: increase CO, Decrease pulmonary edema.
-
Vasodialators
Pimobendan (_________________)
_________ Inotrope
TX:
Vasodialators
Pimobendan ( Vetmedin)Positive Inotrope - vasodialator - TX: CHF, Mitral Valve DZ
-
Other
1. Furosemide (_____________)
Type:
TX:
2. Hydrocodone (______________)
Type:
TX:
3. Theophylline (________, __________)
Type:
TX:
- Other
- 1. Furosemide (Lasix)
- Type: Diuretic
- TX: Pulmonary Edema
- 2. Hydrocodone (Hycodan)
- Type: Narcotic
- TX: Cardiac Cough
- 3. Theophylline (Theolair, Uniphyl)
- Type: Bronchodialator
- TX: Asthma, CHF, Pulmonary Edema
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